IRCT20190506043492N2 IRCT 2020-05-23 Ahvaz University of Medical Sciences the effect of N-acetyl cysteine on liver function after open heart surgery Investigation of the effect of N-acetyl cysteine on liver function after open heart surgery 2018-04-21 anticipated 60 Complete https://irct.ir/trial/47465 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients were randomly selected and divided into two groups of interventions (recipient of N-acetyl cysteine) and control (normal recipient of saline) through a table of random numbers assigned to even numbers for the intervention group and individual numbers for the control group, Blinding description: In this study, patients were unaware that they were in the receiving group of N-acetyl cysteine or normal saline, The person injecting the drug did not know if the syringe contained N-acetyl cysteine or normal saline, Because the drug was taken by another anesthesiologist and labeled 1 and 2, and Finally, the person who took the blood sample from the patients for liver tests did not know the type of intervention and the type of medicine that had been injected for the patients. 3 Liver diseas. Intervention 1: Intervention group: After induction of anesthesia and intubation, they will receive 150 mg / kg n-acetylcysteine intravenously (Oxy-Nak, Elixir Pharmacy, Boroujerd, Iran). Intervention 2: Control group: After induction of anesthesia and intubation, intravenous administration of 150 mg / kg normal saline will be given. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.