IRCT20120215009014N353 IRCT 2020-04-27 Hamedan University of Medical Sciences Effect of plasma of patients recovered from covid-19 versus control group on treatment of covid-19 Effect of plasma of patients recovered from covid-19 versus control group on treatment of covid-19: a randomized clinical trial 2020-05-14 anticipated 100 Complete https://irct.ir/trial/47501 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients will be randomly assigned to intervention and control groups using block randomization. For this purpose, we will prepare four sheets of paper, writing on two sheets the name of the intervention and on the other two sheets the name of the control. The paper sheets will be pooled, placed in a container, and randomly drawn one at a time for each patient without replacement until all four sheets are drawn. The four paper sheets will be then placed back into the container, and this action repeated until the sample size is reached. 2 COVID-19. Intervention 1: Intervention group: Routine care (For outpatients: 250 mg chloroquine tablets every 12 hours for the first day and then every day for up to 6 days; for inpatients: tablet Lupinavir 200 mg and tablet Ritonavir 50 mg every 12 hours for 14 days) plus plasma of patients recovered from covid-19 500 U every week for at least 3 weeks. Intervention 2: Control group: Just routine care (For outpatients: 250 mg chloroquine tablets every 12 hours for the first day and then every day for up to 6 days; for inpatients: tablet Lupinavir 200 mg and tablet Ritonavir 50 mg every 12 hours for 14 days). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situations and the results of the study as well as the approval of the financial supporting organization.