IRCT20190810044500N19 IRCT 2021-08-22 Yazd University of Medical Sciences Evaluation of nitroglycerine and lidocaine ointment on the pain caused by catheterization in neonates Investigation of the effect of 2% nitroglycerin ointment - 2% lidocaine on the pain control due to intravenous catheter in infants; randomized double-blind clinical trial 2021-08-23 anticipated 84 Complete https://irct.ir/trial/47524 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, 84 patients are randomly allocated into two treatment groups (A and B). Block randomization method will be used for random allocation. Fourteen blocks of six are considered. The generated permutations include the letters A and B, which are repeated thrice (for example, ABBABA) in each permutation. These permutations are generated using Random allocation software version 1. For this purpose, the generated list by the software is from 1 to 84, which are arranged in 14 blocks of six in order. To run this software output, we give the first qualified person number 1 and the last person will receive number 84. To consider blinding in random allocation, the list is given to another person outside the study and using short message service (SMS) before assigning the type of treatment according to the number of eligible people is asked and thus people enter the study. In addition, in the software output, both numbers 1 to 84 and the permutations of the letters A and B can be seen, Blinding description: The steps will be covered from the perspective of the patient, the treating physicianو, and the assessors. The first presenter identifies the sequence of assignments of patients according to the order of entry of the patients into the study, and puts the ointments (combination of nitroglycerin-lidocaine or placebo) into one-size boxes for patient use, and identifies them with A or B codes. The student then delivers the drugs to each individual patient. 3 Measurement of pain during catheterization in infants. Intervention 1: Intervention group: Topical nitroglycerin ointment 2% - lidocaine 2%, one gram with an area of one square centimeter, on the infant venous site, apply and then wait for 10 minutes and then clean the site and venipuncture is performed and the amount Pain is measured. Intervention 2: Control group: Placebo ointment consisting of white wax and Vaseline made by Speedro company, 1gram with an area of one square centimeter, is applied on the infant venous site, and then wait for 10 minutes, after which the site is cleansed and venipuncture is performed and the pain is measured. Placebo ointment will be made in the Pharmaceutics Laboratory of Yazd School of Pharmacy. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.