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IRCT20200503047281N1 IRCT 2020-07-25 Yazd University of Medical Sciences Evaluation of Convalescent Plasma Therapy for COVID-19 Patients Evaluation of Convalescent Plasma Therapy for COVID-19 Patients 2020-09-22 anticipated 40 Complete https://irct.ir/trial/47632 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization is done using a table of random numbers. In this method, all patients who meet the inclusion criteria are assigned a number from the file number and these numbers are randomly placed in the table of numbers. Then 20 numbers without the possibility of replacement as an intervention group and 20 people as the control group will be selected. 0 (exploratory trials) COVID-19. Intervention 1: Intervention group: 20 patients are in the severe stage of the disease who receive plasma therapy with intravenous injection dose twice (200 ml per dose) and in addition to routine medical care. Intervention 2: Control group: 20 patients admitted to the severe stage of the disease who did not receive plasma therapy and receive only routine medical care. Yes - There is a plan to make this available What will be shared: All data can be published after coding and unidentifiable and privacy. When: after article publication To whom: All researchers specialize in related fields Conditions: In order to use the results by the scientific community of the world, the information can be published after printing and by observing the coding and confidentiality of the participants in the study upon request. Where to obtain: To the first author or the corresponding person of the published article through their email Dr. Hossein Hadi Nodoshan.hhadin2000@gmail.com How to obtain: The request and how to use the data must be explained by e-mail to the author responsible for the article, which will be received as soon as possible. Comments:
public Dr. Hossein Hadinedoushan
Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Yazd Iran (Islamic Republic of) 8916188635 +98 35 3628 5406 hhadin2000@gmail.com Yazd University of Medical Sciences scientific Dr.Hossein Hadinedoushan
School of Paramedical Sciences, Imam Reza Educational and Research Complex, Daneshjoo Blvd., Imam Hossein Square, Yazd, Iran
Yazd Iran (Islamic Republic of) 8916188635 +98 35 3628 5406 hhadin2000@gmail.com Yazd University of Medical Sciences Iran (Islamic Republic of) age between 20 to 60 years old 20 years 60 years Both People with a history of other immune, genetic or infectious diseases other than corona Individual suspended but negative for clinical standard covid-19 test U07.1 COVID-19 Treatment - Drugs N/A Intervention group: 20 patients are in the severe stage of the disease who receive plasma therapy with intravenous injection dose twice (200 ml per dose) and in addition to routine medical care. Control group: 20 patients admitted to the severe stage of the disease who did not receive plasma therapy and receive only routine medical care. Percentage of patients discharged from the intensive care unit and hospital. Timepoint: Measurement of all standard clinical signs of the disease before the start of plasma therapy and after the start of each injection of plasma over specific intervals of up to one year (if surviving). Method of measurement: Patient file information. Patient mortality rate. Timepoint: Recording the mortality rate for one year after starting plasma therapy. Method of measurement: Patient file information. Yazd University of Medical Sciences Approved 2020-04-12 Ethics committee of Shahid Sadoughi University of MEdical Sciences Daneshjoo Blv. reproductive immuology research center, Shadid Sadoughi University ,Yazd,Iran yazd Yazd Iran (Islamic Republic of)