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IRCT20100621004224N38 IRCT 2020-05-13 Esfahan University of Medical Sciences Effects of sevoflurane with Remifentanil plus Propofol on recovery conditions Comparison of the effects of sevoflurane with Remifentanil plus Propofol on recovery conditions in adolescent patient with movement disorders candidate for dental treatment under general anesthesia. 2020-05-26 anticipated 30 Complete https://irct.ir/trial/47983 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Balanced block randomization, Blinding description: This study is double blind and the injecting person and the person evaluating the recovery conditions are different. For this purpose, an out-of-study person is used to assess recovery conditions.The person evaluating the recovery conditions is not aware of the medication used for anesthesia. Participants are also unaware of the type of drug injected. 3 Movement disorders. Intervention 1: Intervention group: to maintain anesthesia, sevoflurane USP inhaled drug from Piramal Company is used. The drug is given to the patient at a dose of MAC: 1.85 through a tracheal tube with a vaporizer for the drug sevoflurane. Intervention 2: Control group: To maintain anesthesia, Rimifentanil is taken with Propofol (Propofol: 3 mg / kg body weight, followed by Remifentanil: 1 μg / kg body weight per minute). Depending on whether the patient is shaking or shows signs of alertness in response to the situation, further injection of the drug (remifentanil: 0.5 μg per kg body weight or propofol 0.5-1 mg / kg body weight) is done. The drugs are injected within 10-15 seconds. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Naser Kaviani
Faculty of Dentistry, Isfahan University of Medical Sciences, Hezarjerib Ave., Isfehan Town,
Isfehan Iran (Islamic Republic of) 8174673461 +98 31 3673 3504 kaviani@dnt.mui.ac.ir Esfahan University of Medical Sciences scientific Naser Kaviani
Faculty of Dentistry, Isfahan University of Medical Sciences, Hezarjerib Ave., Isfehan Town,
Isfehan Iran (Islamic Republic of) 8174673461 +98 31 3792 5558 kaviani@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) The desire to participate in the study Patients over 18 years of age Patients with movement disorders Patients are candidates for dental treatment under general anesthesia 18 years no limit Both People who are allergic to eggs or soy Known allergies Chronic diseases including heart disease, bleeding disorders, liver disease and kidney disease Other Other Intervention group: to maintain anesthesia, sevoflurane USP inhaled drug from Piramal Company is used. The drug is given to the patient at a dose of MAC: 1.85 through a tracheal tube with a vaporizer for the drug sevoflurane. Control group: To maintain anesthesia, Rimifentanil is taken with Propofol (Propofol: 3 mg / kg body weight, followed by Remifentanil: 1 μg / kg body weight per minute). Depending on whether the patient is shaking or shows signs of alertness in response to the situation, further injection of the drug (remifentanil: 0.5 μg per kg body weight or propofol 0.5-1 mg / kg body weight) is done. The drugs are injected within 10-15 seconds. Recovery score on "Nursing Delirium Screening Scale" Checklist. Timepoint: 5,10 and 15 minuts after entering recovery. Method of measurement: "Nursing Delirium Screening Scale" Checklist. Esfahan University of Medical Sciences Approved 2020-02-23 Ethics Committee of Isfehan University of Medical Sciences Faculty of Dentistry, Isfahan University of Medical Sciences, Hezarjerib Ave., Isfehan Town, Isfehsn Isfehan Iran (Islamic Republic of)