IRCT20151002024290N2 IRCT 2020-05-25 Arak University of Medical Sciences The effect of Shiatsu massage in patients with breast cancer under chemotherapy Effect of Shiatsu massage on physiological parameters ,anxiety and pain during chemotherapy in patients with breast cancer 2020-06-21 anticipated 72 Complete https://irct.ir/trial/48094 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: After selecting the samples by random sampling method, they will be randomly and according to the table of random numbers in the two groups of test and control. In order to randomize the selection of 72 patients into two intervention and control groups, first 9 different blocks of 8 letters T and C are created, which indicate the intervention and control groups (4 people belonging to the intervention group and 4 people). Belong to the control group. These blocks are then randomly selected by drawing lots to obtain a 72-bit combination of blocks, respectively. The resulting combination of letters is placed one by one in 72 closed envelopes, respectively, and with the visit of each patient, one envelope is opened in order to determine in which group the patient is placed, Blinding description: It should be noted that the nurse who will measure vital signs and the level of anxiety and pain of the patient through the Spielberger questionnaire tool and the visual scale of pain will be unaware of the type of intervention being performed. N/A Breast Cancer. Intervention 1: Intervention group:For the intervention group, during chemotherapy, a one-time Shiatso massage will be performed on the Hugo spots for 5 minutes and 2 minutes of rest for up to 20 minutes. The amount of pain, anxiety and physiological signs will be measured before and immediately after the intervention by tools and questionnaires. Intervention 2: Control group: Patients in the control group do not receive any Shiatsu massage intervention on the part of the researcher. In this group, only touch without pressure will be done for 20 minutes. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is "No further information"