IRCT20200519047516N1 IRCT 2020-07-24 Islamic Azad University Comparison of the antifungal effect of Curcumin and Nystatin in treatment of fungous associated with removable prothesis Comparison of antifungal effect of Curcumin and Nystatin in denture stomatitis type 2 and type 3 2020-10-06 anticipated 32 Complete https://irct.ir/trial/48364 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, patients will have two types of denture stomatitis 2 and 3, and to prevent the accumulation of a type of denturestomatitis in a group and its negative impact on the results, the Stratified block randomized method will be used and 32 envelopes are numbered by statistical consultant and the interventions are given to the patients without the knowledge of the researcher of the contents of the envelopes containing the therapeutic intervention and the researcher will not be aware of the contents of the envelope and the intervention made for each group, Blinding description: In this study, after informing the patient of the type of study, and filling out the drug consent form with the help of another person other than the researcher and according to the random numbers determined by the statistical consultant (2 series No. 1 to 16 for Dentuer Stomatitis Type 2 and 3) It will be given to patients. 3 Denture stomatitis. Intervention 1: Intervention group: drug(Curcumin drops prepared from the active ingredient of curcumin in the pharmacology department of the Faculty of Pharmacy, Islamic Azad University-5 cc -4 times in day for 2 weeks- wash the mouth). Intervention 2: Control group: standard drug(Nyststin suspension100000 unit/ml emad company- 40 drops-4 times in day for 2 weeks- wash the mouth ). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more further information