IRCT20161021030410N3 IRCT 2020-06-06 Babol University of Medical Sciences The effect of ischemic preconditioning on myocardial protection Evaluation of the effect of Ischemic preconditioning on myocardial protection in patients undergoing coronary artery bypass graft surgery 2020-01-20 anticipated 150 Complete https://irct.ir/trial/48520 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Samples will be divided into Three groups using Permuted Block Randomization. Number will be selected for allocation concealment by one of the colleagues and by another, that assignment chain is chosen. 2 Cardiovascular Disease. Intervention 1: Control group: In the control group, routine after heparin and cannulation of the aorta and right atrium and start the pump, aortic clamping and injection cardioplegin the aortic root and inducing arrest of the heart, anastomosis distal to the vascular coronary and after turning clamp of perfect for the partial, proximal anastomosis will be performed. Intervention 2: Intervention group: In second group three repetitive episodes of 1 min ischemia separated by 1 min of reperfusion (at systemic pressure) will be applied on coronary artery Then the clamp will be released completely. Intervention 3: Intervention group: In third group, controlled perfusion pressure and post conditioning will be applied together during reperfusion of coronary artery. No - There is not a plan to make this available Justification or reason for not sharing IPD is .