IRCT20160307026950N24 IRCT 2020-09-19 Esfahan University of Medical Sciences Effect of Ephedrine and Ketamine on rapid sequence intubation using Priming Dose of Cis-Atracurium Comparison of the effectiveness of low-dose Ephedrine and Ketamine injections on rapid sequence intubation using Priming Dose of Cis-Atracurium in patients under general anesthesia 2020-06-21 anticipated 128 Complete https://irct.ir/trial/48538 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Diagnostic, Randomization description: Randomization is done in a simple way so that the names of patients enter the randomization software (https://random-allocation-software.software.informer.com/2.0/) if they have the necessary conditions and according to the time of entry. software Randomly assign numbers to each patient, and based on these numbers, patients enter one of the intervention or control groups so that their number reaches the required number in each group, Blinding description: Four packs of drugs A, B, C, D are prepared, each of which contains coded syringes of one shape, and for each patient, a syringe is selected from the packs according to their selected group. And is injected into the patient, the prescriber (anesthesiologist), and the person who records the symptoms Also, patients are unaware of the prescribed drug and therefore both parties are blind. 3 Rapid sequence intubation. Intervention 1: Intervention group E: each patient is injected with Ephedrine 70 Mcr gr/kg before induction. Intervention 2: Intervention group: K: That each patient is injected with 0.5 mg/kg Ketamine before induction. Intervention 3: Intervention group E + K: each patient is injected with 70 micro grams of Ephedrine and 0.5 mg of Ketamine per kilogram of body weight before induction. Intervention 4: Control group N: Normal saline is injected into the patient before induction. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.