IRCT20200530047600N1 IRCT 2020-07-18 Mashhad University of Medical Sciences Evaluation of the effect of Foeniculum vulgare fruit and Echium amoenum Flower Combination on the severity of Physical and psychological symptoms of premenstrual syndrome Evaluation of the effect of Foeniculum vulgare fruit and Echium amoenum Flower Combination on the severity of Physical and psychological symptoms of premenstrual syndrome 2021-09-23 anticipated 80 Complete https://irct.ir/trial/48541 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Permuted block randomization Unit: Individual It is not stratified Tools: random allocation statistical software Regarding concealment: A person outside the design will prepare sealed envelopes based on the random allocation sequence created and provide them to the executors, Blinding description: The same capsules, with the same number, are placed in similar enveloped envelopes (from 1 to 80) based on a random assignment list by a person outside the research design.The study subjects receive the capsules monthly and in envelopes with the code. Participants, researchers, data evaluators, and data analysts are unaware of how the code is assigned. 3 Premenstrual Syndrome. Intervention 1: Intervention group: The test group received oral capsules containing Echium and fennel at a dose of 2 grams of Echium and 1 gram of fennel fruit (Ground and granulated) during the day, three times a day with a glass of lukewarm water for the second two weeks of Cycle in two consecutive cycles. Intervention 2: Control group: The control group will receive a placebo capsule containing starch with the conditions of the intervention group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is اطلاعات بیشتری وجود ندارد