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IRCT20200608047695N1 IRCT 2022-01-20 Ilam University of Medical Sciences Comparison of the effect of licorice vaginal cream and estrogen vaginal cream on the sexual function of postmenopausal women Comparison of the effect of licorice vaginal cream and estrogen vaginal cream on the sexual function of postmenopausal women 2020-07-20 anticipated 82 Complete https://irct.ir/trial/48750 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, we will use the finite randomization method because we want the study groups to have an equal sample size. One of the methods used for finite randomization is the block method. In this study, we use the quadratic block method. The four blocks will consist of two participants in the estrogen group and two participants in the licorice group. And the execution method will be that the possible modes for a block of 4 are 6 modes: a. aabb b. abab ج. abba د. bbaa ه. baba خ. baab and to generate random numbers, we use the online kitset software, by first registering the required values ​​from 1 to 6 (number of numbers 6), and we repeat this 4 times, but in the fourth time the number We put the numbers instead of 6, 2, because in the first 3 times we have produced 18 numbers, and in the last step only 2 more numbers are needed, and thus 20 random numbers between 1 and 6 are produced, which indicate 4 blocks. According to each number, the treatment allocation list is determined. According to the number of samples, which is 82 people, we form 20 blocks of 4 and the last 2 people are randomly divided into two groups. (A = estrogen group, b = licorice group). 2 Sexual function of postmenopausal women. Intervention 1: First Intervention Group: Receipt of vaginal licorice cream, prepared by the University Pharmacology Research Center, Approved dose of gynecologist, use at night with the applicator, The duration of use is 14 days, then 10 days of rest and 14 days of drug re-use. Intervention 2: Receiving 2% estrogen vaginal cream, Approved dose of gynecologist, use at night with the applicator, The duration of use is 14 days, then 10 days of rest and 14 days of drug re-use. Yes - There is a plan to make this available What will be shared: 1-Study protocol 2- Study result When: After completing the study To whom: 1- Faculty members 2- Clinical nurses 3- Medical and nursing students Conditions: Access to data or documentation is possible for the following condition: 1- Use in future study resources 2- Future studies Where to obtain: Please contact parisa ahmadizad Ahmadizad gmail: P.ahmadizaddd@gmail.com How to obtain: After sending the email to parisa ahmadizad, the email will be answered as soon as possible Comments:
public Parisa ahmadizad
Tajarian6, chalimar
Ilam Iran (Islamic Republic of) 6931156381 +98 84 3222 7567 p.ahmadizaddd@gmail.com Ilam University of Medical Sciences scientific Masoume shohani
Pajohesh Blvd, Bangangab Ave, Ilam
Ilam Iran (Islamic Republic of) 6939177143 +98 84 3222 7134 Msh282000@gmail.com Ilam University of Medical Sciences Iran (Islamic Republic of) 1- At least one year has passed since the onset of menopause and a maximum of 8 years since the onset of menopause Gynecologist confirms that menopause must have occurred Vaginal atrophy symptoms (dryness, paleness and Dyspareunia) Married womens Have sex at least 2 times a month during research Literacy for reading and writing Body mass index between 20 and 30 Sexual dysfunction no limit no limit Female Treatment with hormonal drugs Mental illness in the participant or his / her spouse Underlying diseases such as depression, cancers, pulmonary embolism, diabetes Taking anticholinergic drugs F52 Sexual dysfunction not due to a substance or known physiological condition Treatment - Drugs Treatment - Drugs First Intervention Group: Receipt of vaginal licorice cream, prepared by the University Pharmacology Research Center, Approved dose of gynecologist, use at night with the applicator, The duration of use is 14 days, then 10 days of rest and 14 days of drug re-use. Receiving 2% estrogen vaginal cream, Approved dose of gynecologist, use at night with the applicator, The duration of use is 14 days, then 10 days of rest and 14 days of drug re-use. Sexual function. Timepoint: During the study (first day of referral, 30 days after the start of the intervention, 60 days after the start of the intervention). Method of measurement: Female Sexual function Index Questionnaire. Ilam University of Medical Sciences Approved 2020-06-22 Ethics Committee of Ilam University of Medical Sciences Tajarian6, Tajatian street, Chalimar Ilam Ilam Iran (Islamic Republic of)