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IRCT20200612047743N1 IRCT 2021-06-22 Shahid Beheshti University of Medical Sciences Effect of vitamin D3 in rise of hemoglobin Correlation between high dose of vitamin D3 and rise of hemoglobin in mechanical ventilation patients in medical ICU 2021-06-22 anticipated 100 Complete https://irct.ir/trial/49002 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Randomization method: Simple randomization -Randomization unit: individual -Randomization tool: Randomization will be done using the site https://www.randomizer.org which using random numbers extracted by the software, patients will be given one of the two groups of Vitamin D and control. Input software: number of sets (in our study a set of 100) Number of samples in each set (100 samples in total) The range of data in each set (in our study from 1 to 2, ie 1 group therapy and 2 placebo groups, separation from 50 to 1 50 to 2) Output software: one set of 100 numbers from 1 to 2 that are placed in the treatment group or placebo at the time of infection using these 1 and 2 drug codes, Blinding description: Drugs for both groups will be prepared and coded by one of the researchers in the study. Participants in the study who enter the study after obtaining informed consent. In this study, the first group of patients was given oral vitamin D and the second group was given a placebo. The patients' blood samples were taken and their hemoglobin was checked by ICU doctors, who did not know which vitamin D disease or which placebo they were taking. 3 Vitamin D deficiency to prevent anemia in patients undergoing mechanical ventilation. Intervention 1: Intervention group: The treatment method in this study is vitamin D injection (a fat-soluble supplement that is effective in absorbing calcium, phosphate and magnesium in the intestine. It is effective in strengthening bones and teeth by balancing calcium and phosphorus in the body and reducing their renal excretion). At a dose of 50,000 units for 5 days of gavage. One of the several benefits of vitamin D is the treatment or improvement of anemia, which in this study, with the aim of increasing the patient's hemoglobin, patients receive vitamin D. Intervention 2: Control group: Placebo. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public sara salarian
Imam Hossein Hospital, Shahid Madani St
tehran Iran (Islamic Republic of) 1617763141 +98 21 7756 7840 sarasalarian@yahoo.com Shahid Beheshti University of Medical Sciences scientific Sara Salarian
Imam Hossein Hospital, Shahid Madani St
tehran Iran (Islamic Republic of) 1617763141 +98 21 7756 7840 sarasalarian@yahoo.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) patients under mechanical ventilation in ICU Non surgical patients 18 years no limit Both Non mechanical ventilated patients anemia Chronic kidney and liver disease Abnormal deficiency and increase of vitamin D3 Patients discharged from the ICU before 12 days R82.3 Prevention N/A Intervention group: The treatment method in this study is vitamin D injection (a fat-soluble supplement that is effective in absorbing calcium, phosphate and magnesium in the intestine. It is effective in strengthening bones and teeth by balancing calcium and phosphorus in the body and reducing their renal excretion). At a dose of 50,000 units for 5 days of gavage. One of the several benefits of vitamin D is the treatment or improvement of anemia, which in this study, with the aim of increasing the patient's hemoglobin, patients receive vitamin D. Control group: Placebo Patient hemoglobin level. Timepoint: First, study the hemoglobin concentration and vitamin D3 levels. The patient's hemoglobin level is then recorded one week after the intervention. Hemoglobin will be measured and recorded once a week for a maximum of one month. Method of measurement: Flow measures the hemoglobin level by a blood test. Shahid Beheshti University of Medical Sciences Approved 2019-05-21 Ethics committee of Shahid Beheshtee University of Medical Sciences Shahid Beheshti University of Medical Sciences, Shahid Erabi St, Ebne Yaman St, Shahid Chamran Highway, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)