IRCT20200616047799N1 IRCT 2020-08-23 Shahid Beheshti University of Medical Sciences Photobiomodulation anti-inflammatory effect in COVID-19 Comparison of serum inflammatory mediators levels in patients affected by COVID-19 with and without photobiomodulation (PBM) 2020-06-30 anticipated 40 Complete https://irct.ir/trial/49012 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Every patient is given a code at the first step of hospitalization. We use the last digit of the code which is odds or even to randomize the patients. This will be simple randomization for each person separately, Blinding description: We will use turned-on device for the participants who are in the intervention group while the control group will use the turned-off device. 1-2 COVID-19. Intervention 1: Intervention group: Photobiomodulation with red light on patients' chest , back and neck for 3 days each day for 15 minutes. The device named "Neolys" manufactured by "Life+" company in France. Intervention 2: Control group: The device is used for the intervention body location every day for 3 days each for 15 minutes but the device will not be turned-on. Yes - There is a plan to make this available What will be shared: Data set will be very hardly shared if necessary and in specific condition. When: Immediately after publishing all the planned articles. To whom: Related researchers who necessarily need the data will be gave them. Conditions: Research ethics and research rights have to be considered in this regard. Where to obtain: The affiliations of the authors would be available when the articles published. How to obtain: The corresponding author would be available by email and will explain the prerequisites and time to give the data. Comments: