]>
IRCT20200617047814N1 IRCT 2020-07-04 Tehran University of Medical Sciences Remote Ischemic preconditioning effect for prevention of contrast-induced nephropathy Remote Ischemic preconditioning effect for prevention of contrast-induced nephropathy in patients with coronary angiography/angioplasty 2020-06-21 anticipated 200 Complete https://irct.ir/trial/49028 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patient block randomization is performed using the website www.randomization.com, and patient codes are generated with envelope letters in which the data is not clear, and each of the random questions generated is recorded on a single card and the card is inserted into the packet, Blinding description: In the method, none of the patients and angiography/angioplasty operators and researcher will be aware of patient coding and grouping. The clinical caregiver performs the intervention in the intervention group. N/A Contrast induced nephropathy. Intervention 1: Intervention group: In the intervention group, 45 minutes before angiography/angioplasty under induction ischemia with blood pressure cuff in the elbow area by inflating the cuff 50 mm Hg above systolic pressure in 5-minute for 4 cycles and 5-minute emptying between cycles with hydration. Standard treatment (hydration) is performed for all patients in the intervention and control group. If creatinine increases more than 0.5 mg / dL or eGFR decreases, more than 25% of contrast-enhanced nephropathy is considered. Intervention 2: Control group: In the control group, 45 minutes before angiography / angioplasty, inflating the 10 mm Hg pressure gauge cuff is performed less than systolic pressure in the elbow area with standard treatment. If creatinine increases more than 0.5 mg / dL or eGFR decreases, more than 25% of contrast-enhanced nephropathy is considered. Yes - There is a plan to make this available What will be shared: All data can be shared after people have not been identified. When: Immediately after the publication of the results. To whom: Researchers working in academic and scientific institutions. Conditions: Any analysis is allowed. Where to obtain: seyed shafi shafipoor milad.shafipoor@gmail.com How to obtain: If the article is published, the data will be given as soon as possible after the request. Comments:
public Seyed Shafi Shafipoor
Dr. Shariati hospital, North Karegar Ave, Jalal-e-Al-e-Ahmad Hwy
Tehran Iran (Islamic Republic of) 1411713135 +98 21 8490 1000 milad.shafipoor@gmail.com Tehran University of Medical Sciences scientific Seyed Abdolhossein Tabatabaie
Dr. Shariati hospital, North Karegar Ave, Jalal-e-Al-e-Ahmad Hwy
Tehran Iran (Islamic Republic of) 1411713135 +98 21 8490 1000 tabatabaeiseyedah@gmail.com Tehran University of Medical Sciences Iran (Islamic Republic of) Cr > 1.4mg/dl or eGFR< 60 cc/min Informed consent 18 years no limit Both hemodialysis or Peritoneal dialysis N99.0 Postprocedural (acute) (chronic) kidney failure Prevention Prevention Intervention group: In the intervention group, 45 minutes before angiography/angioplasty under induction ischemia with blood pressure cuff in the elbow area by inflating the cuff 50 mm Hg above systolic pressure in 5-minute for 4 cycles and 5-minute emptying between cycles with hydration. Standard treatment (hydration) is performed for all patients in the intervention and control group. If creatinine increases more than 0.5 mg / dL or eGFR decreases, more than 25% of contrast-enhanced nephropathy is considered. Control group: In the control group, 45 minutes before angiography / angioplasty, inflating the 10 mm Hg pressure gauge cuff is performed less than systolic pressure in the elbow area with standard treatment. If creatinine increases more than 0.5 mg / dL or eGFR decreases, more than 25% of contrast-enhanced nephropathy is considered. Cratinine. Timepoint: Before the procedure and 48 hours after the procedure. Method of measurement: blood test: based on mg/dl. EGFR. Timepoint: Before the procedure and 48 hours after the procedure. Method of measurement: blood test: calculated by cockroft furmola. Tehran University of Medical Sciences Approved 2020-03-17 Tehran university of medical sciences pour sina Ave Tehran Tehran Iran (Islamic Republic of)