IRCT20160524028038N6 IRCT 2020-06-30 Yasouj University of Medical Sciences Sildenafil Citrate with melatonin and intrauterine growth restriction Evaluation of the effect of Sildenafil Citrate with melatonin on intrauterine growth restriction 2019-10-20 anticipated 88 Complete https://irct.ir/trial/49187 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method: use block; Random unit: Individual; Randomization tool: Statistical software; Sequence Building: Using randomized 4 in 4 blocks; Hiding method: Use envelopes in the package, Blinding description: The blinding method is patients and physicians will not be aware of their allocation to study groups and all medications will be placed into same capsules of size, shape and color by the pharmacist. N/A Intrauterine growth restriction. Intervention 1: Group A (sildenafil): In this group, sildenafil citrate tablets (Vizarcin), 25 mg orally every eight hours for four weeks. Intervention 2: Group B (Melatonin): In this group, melatonin tablets (Razak Pharmaceutical Company, Iran) are prescribed three mg three times a day (morning, lunch, before bed) for four weeks. Intervention 3: Group C (sildenafil with melatonin): In this group, the drug dose will be the same as the drug group A and B. Intervention 4: Group D: Plasbo drug containing starch is prescribed in the same way as the above intervention groups. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information