IRCT20161219031464N4 IRCT 2020-09-08 Shahid Beheshti University of Medical Sciences Investigation of the effect of pentoxifylline on the prevention of radio contrast nephropathy Evaluation of the effect of oral pentoxifylline on prevention of radiocontrast nephropathy in patient that undergone angiographye 2020-02-20 anticipated 192 Complete https://irct.ir/trial/49208 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: This division is based on a table of random numbers.The method of randomization is simple.According to the table of numbers, patients are divided into two groups: case and control.. Patients who visit on even days will be in the target group and patients who are admitted on odd days will be in the control group, Blinding description: In this study, participants and who evaluated the results and analyzer of the data were blind.Patients who are candidates for angiography are coded according to the schedule.The person encoding is blind about the target and control group .The patient then enters the group based on the received code. Data collection and analysis is done by someone who has no knowledge of the details. 3 Kidney disorders caused by contrast material following angiography. Intervention 1: Intervention group: In this group, they receive normal saline at a dose of one cc per kilogram of body weight and pentoxifylline (400 mg orally every 8 hours) for 12 hours before and 12 hours after angiography,. Intervention 2: Control group: In this group, patients will receive 1 cc of normal serum saline per kilogram of body weight from 12 hours before to 12 hours after angiography. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.