IRCT20200519047506N1 IRCT 2020-09-18 Karaj University of Medical Sciences Evaluation the effect of N Acetyl Cystein (NAC) in myocardial infarction Evaluation the effects of N Acetyl Cysteine (NAC) in myocardial reperfusion of patients with STEMI undergoing to P-PCI in Karaj's Shahid Rajayi hospital in 2020 2020-07-22 anticipated 142 Complete https://irct.ir/trial/49500 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization with a block size of 4 patients which every single block contains the equal groups. There was 6 possible way for randomization in a block. We randomly choose blocks, so the total on A and the total on B only differed by a maximum of 2. So say the first Block is AABB and the total subjects on A and B will be; (1,0), (2,0), (2,1), (2,2), Blinding description: Interventionist and the researcher who analyzes data both use patient's code. Also, title groups were coded with A and B whom none of them know which one is the NAC or control group. 3 Acute myocardial infarction. Intervention 1: Intervention group: 1200 mg N Acetyl Cysteine prior to primary PCI and every 12 hour for 48 hour will be injected intravenously. Intervention 2: Control group: 100 cc serum dextrose 5% prior to primary PCI and every 12 hour for 48 hour will be injected intravenously. Yes - There is a plan to make this available What will be shared: The study protocol, informed consent, study result, and some parts of IPD will be shared. When: 6 month after result edition To whom: Everybody Conditions: No condition needed. Where to obtain: Huma Arabi miss.arabi@yahoo.com How to obtain: After sending email and obtaining identity data information will be accessible in 2 weeks. Comments: