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IRCT20200501047255N1 IRCT 2020-07-27 Shahroud University of Medical Sciences Comparison of intravenous remifentanil and intravenous lidocaine in prevention of cardiovascular response following laryngoscopy and tracheal intubation under genereal anesthesia in limbs surgery. Comparison of intravenous remifentanil and lidocaine on the cardiovascular response to laryngoscopy and tracheal intubation under general anesthesia in open limbs surgery. 2020-05-11 anticipated 60 Complete https://irct.ir/trial/49765 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple blind randomization Which consists of 60 completely identical sheets and is written in 30 sheets of the control group and 30 sheets of intervention and each patient is divided by removing one sheet and the sheet is left out, Blinding description: 60 identical small ball(30 intervension and 30 control) in a bag used for randomization,for each patient one ball randomly took by anesthetist. patient, researcher and data collector were unaware of patient group. 3 Condition 1: Open reduction and internal fixation of ulna and radius fracture. Condition 2: Open reduction of humerus fracture. Condition 3: Open reduction of tibia fractures. Intervention 1: Intervention group: 30of parcipitants that received remifentanil with a dose of 2µg/kg. Intervention 2: Control group: A group of 30 people who received 1.5 micrograms per kilogram of lidocaine weight. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Dr Javad nourian
Shahroud Haft Tir Square Shahroud University of Medical Sciences
Shahroud Iran (Islamic Republic of) 36147_73947 +98 23 3239 5054 Mtkzf.ms@gmail.com Shahroud University of Medical Sciences scientific Dr Javad nourian
Shahroud Haft Tir Square Shahroud University of Medical Sciences
Shahroud Iran (Islamic Republic of) 36147-73947 +98 23 3239 5054 Mtkzf.ms@gmail.com Shahroud University of Medical Sciences Iran (Islamic Republic of) Open limbs surgery under general anesthesia Class 1 and 2 of anesthesia risk (According to American society of anesthesiologist's classification), 18 years 60 years Both Difficult intubation prolonged ( more than 30 seconds) attempts at laryngoscopy Repeated attempts at laryngoscopy S52.4 S42.4 S82.3 Fracture of shaft of radius Fracture of lower end of humerus Fracture of lower end of tibia Treatment - Drugs Treatment - Drugs Intervention group: 30of parcipitants that received remifentanil with a dose of 2µg/kg Control group: A group of 30 people who received 1.5 micrograms per kilogram of lidocaine weight. Blood pressure. Timepoint: Before induction of anesthesia and just following laryngoscopy and tracheal intubation. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor. Pulse rate. Timepoint: Before induction of anesthesia and just following laryngoscopy and tracheal intubation. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor. Shahroud University of Medical Sciences Approved 2020-05-09 Ethics committee of Shahroud university of medical sciences Shahroud university of medical sciences , 7tir sq Shahroud Semnan Iran (Islamic Republic of)