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IRCT20200822048473N1 IRCT 2020-08-24 Babol University of Medical Sciences The effect of fenofibrate on the prevention of neonatal hyperbilirubinemia in mothers with O type blood group The effect of fenofibrate on the prevention of neonatal hyperbilirubinemia in mothers with O type blood group 2020-08-24 anticipated 120 Complete https://irct.ir/trial/50451 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Other, Purpose: Prevention, Randomization description: In this clinical trial study, by simple randomization method and using table of random numbers, 120 patients are divided into two study groups and receive the intervention of the corresponding group, Blinding description: The sampler and the researcher, as the person prescribing the medicine, are aware of the study process, but the neonate is not aware of the study process. 3 Neonatal jaundice. Intervention 1: Intervention group: Fenofibrate is given as a single dose of 10 mg per kg. Intervention 2: Control group: No medicine is given. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Seddighe Norouzian
Babol University of Medical Sciences, Ganjafrooz Street , Babol , Mazandaran ,Iran.
Babol Iran (Islamic Republic of) 4717647745 +98 11 3219 2832 norouzian88s@gmail.com Babol University of Medical Sciences scientific Seyedeh Zahra akbarian Rad
Babol University of Medical Sciences, Ganjafrooz Street, Babol, Mazandaran ,Iran
Babol Iran (Islamic Republic of) 4717647745 +98 11 3219 2832 zhr_akbarian@yahoo.com Babol University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Term neonatal (37 weeks to 41 weeks and 6 days) Neonatal with blood type A or B from mothers with positive O blood type and fathers with A, B or AB blood types Without congenital anomalies, birth trauma and history of resuscitation at birth Neonatal born by elective cesarean section who did not receive induction before delivery Rh incompatibility 1 day 28 days Both P58 Neonatal jaundice due to other excessive hemolysis Prevention Prevention Intervention group: Fenofibrate is given as a single dose of 10 mg per kg. Control group: No medicine is given. Transcutaneous bilirubin level. Timepoint: Measurement of transcutaneous bilirubin levels at the end of 12, 24, 48 and 72 hours after birth and at the time of admission, in both control and fenofibrate groups. Method of measurement: Transcutaneous bilirubin meter. Jaundice leading to hospitalization. Timepoint: During hospitalization. Method of measurement: Blood test. Duration of phototherapy. Timepoint: During hospitalization. Method of measurement: Duration in days. The rate of severe jaundice. Timepoint: During hospitalization. Method of measurement: Blood test. Babol University of Medical Sciences Approved 2020-08-10 Ethics committee of Babol University of Medical Sciences Babol University of Medical Sciences, Ganjafrooz Street, Babol, Mazandaran, Iran Babol Mazandaran Iran (Islamic Republic of)