<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200703047993N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2020-09-28</date_registration>
      <primary_sponsor>Riphah International University</primary_sponsor>
      <public_title>Effects of Active Release Technique and Active Isolated Stretching on the muscles of upper cross syndrome</public_title>
      <acronym>UCS,AIS,ART</acronym>
      <scientific_title>Effects of Active Release Technique and Active Isolated Stretching on the muscles of upper cross syndrome</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2641-06-21</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>34</target_size>
      <recruitment_status>Pending</recruitment_status>
      <url>https://irct.ir/trial/50467</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: , Once the above mentioned inclusion and exclusion criteria will be taken into account, potential participants will be considered. They will be requested to participate in the study. Written informed consent will be taken from Riphah ethical committee. Each participant will be requested to draw either number one or number two from a box. Number one will be allocated to Group A and number two will be allocated to group B, Blinding description: Outcome Assessor will be blinded by labeling the
participants with different codes.</study_design>
      <phase>N/A</phase>
      <hc_freetext>upper cross syndrome.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group :Group A: active release technique. The patients will complete the questionnaire given to them. The researchers screened the participants for tight musculature by testing. To treat muscle with ART, the therapist puts patient in a position so that the muscle is shortened and then applies hands-on tension. Next, they’ll instruct the patient to lengthen while they hold the tension in place. They may apply this combination of tension and motion to several different areas before patient feel the full release. Treatment of active release technique given to subjects in Group A performed by researcher at weekly intervals. subjects received active release technique, 3 sets of 10 repetitions per session 3 sessions per week on alternate days for a period of 16 sessions. Session lasts for 40 minutes, three times a week for 6 weeks. The pre and post visit will involve: The researcher will reassess the patient, After the complete session patients will fill the questionnaire again. The researcher will measure the muscle length and compare with the pre-limanary measurement taken. Intervention 2: Intervention group:             Group B:  active Isolated Stretching. The patients will complete the questionnaire given to them. The researchers screened the participants for tight musculature by testing.•	Treatment of active isolated stretching exercise given to Group B. Perform five to 10 repetitions. The process of holding the stretch for 1-2 seconds is repeated 8-10 times for optimal “melting of the fascia”. This intervention is applied for 3 times a week for 5 weeks or 16 sessions. Session lasts for 40 minutes, three times a week for 6 weeks. The pre and post visit will involve: The researcher will reassess the patient,	After the complete session patients will fill the questionnaire again ,The researcher will measure the muscle length and compare with the pre-limanary measurement taken.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is .</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Fizza Ali Syed</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>House No 4 street No 36 Qilla gujjar singh Lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 42 36297030</telephone>
        <email>fizza.ali.syed@gmail.com</email>
        <affiliation>Riphah international university Lahore</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Fizza Ali Syed</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>House No 4 street No 36 Qilla gujjar singh , Lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 42 36297030</telephone>
        <email>fizza.ali.syed@gmail.com</email>
        <affiliation>Riphah International University Lahore</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>•	Patients from both genders
•	patients of  age 20 to 40 years
•	patients with a score of 4 or more on numerical pain rating scale (NPRS).
•	Cranio-vertebral angle measured less than or equal to 50 degree.</inclusion_criteria>
      <agemin>20 years</agemin>
      <agemax>40 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>•	any inflammatory arthritis including Rheumatoid arthritis, Ankylosing spondylitis,
,•	cervical spine surgery,
,•	cervical spine trauma,
, •	cervical spine instability</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M62.9</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Disorder of muscle, unspecified</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group :Group A: active release technique. The patients will complete the questionnaire given to them. The researchers screened the participants for tight musculature by testing. To treat muscle with ART, the therapist puts patient in a position so that the muscle is shortened and then applies hands-on tension. Next, they’ll instruct the patient to lengthen while they hold the tension in place. They may apply this combination of tension and motion to several different areas before patient feel the full release. Treatment of active release technique given to subjects in Group A performed by researcher at weekly intervals. subjects received active release technique, 3 sets of 10 repetitions per session 3 sessions per week on alternate days for a period of 16 sessions. Session lasts for 40 minutes, three times a week for 6 weeks. The pre and post visit will involve: The researcher will reassess the patient, After the complete session patients will fill the questionnaire again. The researcher will measure the muscle length and compare with the pre-limanary measurement taken.</i_keyword>
      <i_keyword>Intervention group:             Group B:  active Isolated Stretching. The patients will complete the questionnaire given to them. The researchers screened the participants for tight musculature by testing.•	Treatment of active isolated stretching exercise given to Group B. Perform five to 10 repetitions. The process of holding the stretch for 1-2 seconds is repeated 8-10 times for optimal “melting of the fascia”. This intervention is applied for 3 times a week for 5 weeks or 16 sessions. Session lasts for 40 minutes, three times a week for 6 weeks. The pre and post visit will involve: The researcher will reassess the patient,	After the complete session patients will fill the questionnaire again ,The researcher will measure the muscle length and compare with the pre-limanary measurement taken.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>•	Muscle length measurement. Timepoint: baseline, before and after treatment session, 3 sessions per week on alternate days  for a period of 16 sessions. Method of measurement: Vernier calipers and measuring tape.</prim_outcome>
      <prim_outcome>•	Cervical ROM. Timepoint: baseline, before and after treatment session, 3 sessions per week on alternate days  for a period of 16 sessions. Method of measurement: Universal Goniometer.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Function. Timepoint: baseline, before and after treatment session, 3 sessions per week on alternate days  for a period of 16 sessions. Method of measurement: Neck disability index.</sec_outcome>
      <sec_outcome>Forward head posture. Timepoint: baseline, before and after treatment session, 3 sessions per week on alternate days  for a period of 16 sessions. Method of measurement: •	APECS app.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Riphah International University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2641-04-27</approval_date>
        <contact_name>Secretary ethical review committee, Riphah College of Rehabilitation and Allied health Sciences</contact_name>
        <contact_address>28-M, Quaid-e-Azam Industrial Estate, Kot Lakhpat, Lahore. Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
