IRCT20200802048275N1 IRCT 2021-01-06 Iran University of Medical Sciences Effect of gabapentin and pregabalin on pain control after percutaneous nephrolithotomy Comparison of the effect of preoperative administration of gabapentin and pregabalin on pain control after percutaneous nephrolithotomy 2021-01-20 anticipated 66 Complete https://irct.ir/trial/50477 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients receive a random number using the random number table according to their priority entry to the center that matches the numbers on the sealed envelopes. Inside the sealed envelopes is one of the codes A, B and C. A represents the first intervention group that will receive 20 ml of sterile normal saline, B represents the second intervention group that will receive 40 ml of sterile normal saline, and C represents the third intervention group that will receive 60 ml of normal sterile saline. The number of patient in each group is equal, Blinding description: Study participants are not aware of their assigned group and will be unaware of the drug used. Of course, they participate in the study with informed consent. 2 Percutaneous nephrolithotomy. Intervention 1: Intervention group: wo hours before surgery, a 150 mg pregabalin capsule is given. Intervention 2: Intervention group: two hours before surgery, a 300 mg gabapentin capsule is given. Intervention 3: Control group: two hours before surgery, a placebo capsule is given. Yes - There is a plan to make this available What will be shared: All potential data is shared after unidentifiable people. When: Start of access period 6 months after printing results To whom: Researchers working in academic and scientific institutions Conditions: There are no special conditions. Where to obtain: Dr. Massoud Ghorbanloo How to obtain: After reviewing the applicant's request, it will be sent to him. Comments: