IRCT20200902048594N1 IRCT 2020-09-22 Islamic Azad University The effect of Betahistine on nausea and vomiting after surgery The effect of Betahistine on nausea and vomiting after Laparoscopic Cholecystectomy 2020-09-05 anticipated 80 Complete https://irct.ir/trial/50712 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Other, Purpose: Supportive, Other design features: Individuals are randomly divided into two groups, the first group receiving Betahistine and the second group receiving Placebo, Randomization description: Patients are divided into two groups A and B using SPSS software and simple randomization. Group A patients receive placebo and group B patients receive betahistine, Blinding description: Patients are fully aware of the intervention and have sufficient satisfaction, but are unaware of grouping (A, B). After collecting all the data, the information will be analyzed. As stated in the intervention groups, the placebo was an empty drug that looked similar to betahistine. 3 postoperative nausea and vomiting. Intervention 1: Intervention group:Betahistine at a dose of 16 mg from Ecterco factory, which is given to patients 3 hours before laparoscopic cholecystectomy. Intervention 2: Control group: placebo which is prepared as an empty medicine with a betahistine-like appearance prepared in Urmia School of Pharmacy which will be given 3 hours before the operation. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information.