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IRCT20200905048627N1 IRCT 2020-10-16 Mazandaran University of Medical Sciences effect of Anahil Plus and Ibuprofen on pain after root canal treatment Comparison of the analgesic effect of Anahil Plus and ibuprofen on pain after root canal treatment: a clinical trial study 2020-09-19 anticipated 78 Complete https://irct.ir/trial/50742 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: The sampling method is 2-step. In the first step, using a simple random sampling method, samples with inclusion criteria will be selected. In the second stage, the blocked randomization method will be used for random allocation. Using blocked randomization, samples are assigned to two groups. The blocked randomization process is done with random allocation software. The samples will be placed in thirteen hexagonal blocks as mentioned, Blinding description: Due to the type of medication, there is no possibility of double-blinding, so the person who records the pain score is blinded without knowing the type of medication. 2-3 Post endodontic pain. Intervention 1: Intervention group: Anahil Plus capsules containing 150 mg of bromelain and 300 mg of turmeric, Permon Amin Health Company, single dose before endodontic treatment. Intervention 2: Control group: Ibuprofen 400 mg tablet Saponin company single dose before endodontic treatment. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is there is no more information
public Fateme Keshvardoost
Tooba dental clinic, khazar Blv, Sari
Sari Iran (Islamic Republic of) 4816895475 +98 11 3324 4894 F.keshvardoost@yahoo.com Mazandaran University of Medical Sciences scientific Dr Narges Hoshyari
Tooba dental clinic, khazar Blvd, Sari
Sari Iran (Islamic Republic of) 4816895475 +98 11 3324 4894 narjeshoshyari@rocketmail.com Mazandaran University of Medical Sciences Iran (Islamic Republic of) Healthy patients aged 20 to 50 years Posterior teeth with irreversible pulpitis Spontaneous pain with at least 30mm on Visual Analogue Scale Radiographically normal teeth, without any lesions, without sinus tract and without acute periapical abscess Normal patients according to the Hospital Anxiety and Depression Scale Prolonged tooth response to pulp electrical test and Endo-ice test Fill in and sign the consent form 20 years 50 years Both Taking medication that interferes with Non Steroid Anti Inflammatory Drugs or Lidocaine Existence of systemic disease Pregnancy or breastfeeding allergy to pineapple, celery, carrot and fennel Consumers of anticoagulants Existence of aggressive periodontal disease unable to restore the tooth pain in more than one tooth Treatment - Drugs Treatment - Drugs Intervention group: Anahil Plus capsules containing 150 mg of bromelain and 300 mg of turmeric, Permon Amin Health Company, single dose before endodontic treatment Control group: Ibuprofen 400 mg tablet Saponin company single dose before endodontic treatment Pain after endodontic treatment. Timepoint: 6, 12 and 24 hours after endodontic treatment. Method of measurement: Visual Analouge Scale questionnaire. Mazandaran University of Medical Sciences Approved 2020-09-06 Ethics committee of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, Vali-asr Highway, Imam Square, Sari Sari Mazandaran Iran (Islamic Republic of)