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IRCT20200906048636N1 IRCT 2021-12-29 Tabriz University of Medical Sciences acyclovir in anal fissure Evaluation and comparison of therapeutic results of acyclovir in the treatment and improvement of anal fissure in non-herpes simplex virus patients and control group 2021-12-06 anticipated 120 Complete https://irct.ir/trial/51041 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Rand list version 1.2 Software, Blinding description: Patients are divided into 2 groups of 60 people. A group of 60 people called the control group is given known anti-fisher drugs such as diltiazem and the experimental group (including 60 people) will be used acyclovir ointment to treat anti-fissure. Patients' clinical history will be reviewed by phone every day and every week in the clinic and all information will be recorded in the attached questionnaire. 3 Anal fissures. Intervention 1: Intervention group: First group receiving acyclovir ointment as treatment of anal fissure. Intervention 2: Control group: Second group receiving common treatment (diltiazem ointment) of the anal fissure. Yes - There is a plan to make this available What will be shared: All the data including age, sex, history of STD (such as HSV), and the type of treatment used, will be shared anonymously. When: Data will be accessible 6 months following publication of the results To whom: Our documentations will be accessible for academic researchers. Conditions: Any analysis of the data is approved. Where to obtain: Ali Farbod How to obtain: The data will be accessible a maximum of 2 weeks after applying via email to Ali.frbd@gmail.com Comments:
public Ali Farbod
Imam Reza Hospital, Golgasht street, Tabriz
Tabriz Iran (Islamic Republic of) 5166616471 0098413331317 ali.frbd@gmail.com Tabriz University of Medical Sciences scientific Ali Farbod
Imam Reza Hospital, Golgasht Street, Tabriz
Tabriz Iran (Islamic Republic of) 5166614756 +98 41 4334 1317 Ali.frbd@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Patients' informed consent to participate in the study No previous or current history of HSV and other STDs Adults over the age of 18 Referral patients with clinical diagnosis of anal fissure 18 years 80 years Both Have a previous or current history of HSV and other perinatal STDs Patient dissatisfaction to participate in the study K60.2 Anal fissure, unspecified Treatment - Drugs Treatment - Drugs Intervention group: First group receiving acyclovir ointment as treatment of anal fissure Control group: Second group receiving common treatment (diltiazem ointment) of the anal fissure Pain relief assessed based on numerical rating scale (NRS). Timepoint: before intervention and 2, 3 , 4, 8, 12 weeks after intervention. Method of measurement: Checklist based on NRS. Tabriz University of Medical Sciences Approved 2021-12-01 Ethics committee of Tabriz University of Medical Sciences Tabriz University of Medical Sciences, Golgasht Street, Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)