IRCT20150304021338N2 IRCT 2021-02-11 Esfahan University of Medical Sciences Comparison of the effect of oral zinc sulfate on the prevention of chemotherapy-induced oral mucositis Evaluation of the effect of oral zinc sulfate with placebo on the prevention of chemotherapy-induced oral mucositis in patients treated with adriamycin and cyclophosphamide 2021-02-18 anticipated 92 Complete https://irct.ir/trial/51105 interventional Randomization: Not randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Blinding description: In this study, two drugs, oral zinc sulfate and placebo, in terms of shape and color, are prepared in the same way and provided to the researcher. They also prescribe them without knowing the type of any of the drugs. Also, the person recording the clinical and basic information of the patients as well as the statistical analyst will not be aware of the type of intervention. 3 Breast Cancer. Intervention 1: Control group: when starting chemotherapy treatment, patients take two placebo capsules(Alhavi Company) daily with food for 12 weeks. Intervention 2: Intervention group: when starting chemotherapy treatment, patients take two capsules of zinc sulfate (Alhavi Company) daily with food for 12 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information