IRCT20201003048910N1 IRCT 2020-10-18 Tehran University of Medical Sciences Evaluation of the effect of oral and vaginal isosorbide mononitrate tablets and oral propranolol tablets on cervical preparation. Evaluation of the effect of oral and vaginal isosorbide mononitrate and oral propranolol tablets on cervical preparation before induction in primiparous and term pregnancy 2018-09-23 anticipated 120 Complete https://irct.ir/trial/51380 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Screening, Randomization description: The primiparous term pregnancy who needed induction of labor due to termination of pregnancy and adverse cervix were easily selected and based on a random number table into four groups of recipients of forty mg isosorbide vaginal mononitrate (n = 30) and oral isosorbide mononitrate. Forty mg (30) patients and 40 mg oral propranolol tablets (two 20 mg tablets every twelve hours to the dose (n = 30) and the control group (n = 30) were divided, Blinding description: The person assessing the consequences is kept blind. 3 cervical ripening. Intervention 1: In the first group, single dose of 40 mg of isosorbide mononitrate from Aria drug will be placed vaginally in the posterior fornix by the researcher. Intervention 2: In the second group single dose of 40 mg Isosorbide mononitrate tablets are given orally from Aria Pharmaceutical Company. Intervention 3: Oral propranolol tablets are given orally at single dose of 20 mg from Dr. Obidi Pharmaceutical Company. Intervention 4: Control group: The control group is given 24 hours to soften the cervix and no medication is prescribed. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.