IRCT20201014049024N1 IRCT 2020-11-09 Ahvaz University of Medical Sciences The effect of Goal-directed fluid therapy on intraoperative transfusion rate in spine surgery The effect of Goal-directed fluid therapy on intraoperative transfusion rate in spine surgery in Golestan Hospital in 1399 2020-04-21 anticipated 60 Complete https://irct.ir/trial/51867 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients who are candidates for spinal surgery will be selected by census according to the inclusion criteria and will be treated randomly using envelopes containing a code A (Targeted fluid therapy group) and B (Routine fluid therapy group), Blinding description: Due to the double-blindness of the study, patients did not know whether they were in the routine or targeted fluid therapy group, and the recorder was unaware of whether the patients were in the study group or controls, and the statistical analyzer was unaware of the grouping and injection solution. 3 Patients undergoing spinal surgery due to spinal canal stenosis or other causes.. Intervention 1: Intervention group: For patients in the intervention group, targeted fluid therapy will be performed according to the protocol. Before induction, 4 mg / kg of crystalloid solution (Ringer) is given and then the hemodynamic invasive monitoring device will be installed through the radial artery, which is given crystalloid based on the variance of the impact volume of the therapeutic fluid. Intervention 2: Control group: Patients in the control group will undergo conventional fluid therapy using the 4-2-2 mg / kg / h rule at a rate of 10 ml / kg / hr crystalloid (normal saline / Ringer serum). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.