]>
IRCT20200622047874N1 IRCT 2021-02-15 Esfahan University of Medical Sciences Effect of vitamin D on improvement of n 5-10 years old children with idiopathic short stracture Effect of vitamin D on serum level of Insulin-like growth factor 1 in 5-10 years old children with idiopathic short stature 2021-04-21 anticipated 28 Complete https://irct.ir/trial/51991 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization of patients in both groups is done using random allocation software. In the mentioned software, the total number of sample size and the number of groups are entered and the software output includes a list that has randomly distributed the total sample size in two groups according to the number. Patients are distributed in two groups according to the time of referral according to the list, Blinding description: After obtaining permission from the University Medical Ethics Committee, the researcher referred to the endocrinology clinic of Imam Hossein Hospital, found children with inclusion criteria, explained the objectives of the research to the patients' parents, and after obtaining written consent, 5 ml of blood sample. Intravenously will be taken from children to measure 25-hydroxy vitamin D and IGF-1 levels. 3 Idiopathic Short Stracture. Intervention 1: Intervention group1: Children with vitamin D levels less than 29 ng / ml will be treated with 50,000 units of vitamin D supplement per week for 8 weeks. Vitamin D and IGF-1 levels will be measured again 3 months after starting treatment. Intervention 2: Control group: In this group, routine care measures are performed and no intervention is performed. Only vitamin D levels and insulin-like growth factor were measured at the beginning and end of the study, and the results were compared with the intervention group. No - There is not a plan to make this available Justification or reason for not sharing IPD is The plan belongs to a government agency and cannot be shared.
public Elham Hashemi
Hezarjareeb
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3620 2020 hashemielham@yahoo.com Esfahan University of Medical Sciences scientific Elham Hashemi
Hezarjareeb
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3620 2020 hashemielham@yahoo.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Idiopathic short stracture Age range 5-10 years Low IGF-1 level Parental consent for interewd to study 5 years 10 years Both Vitamin D level less than 29 ng / ml R62.52 Idiopathic Short Stracture Treatment - Drugs Placebo Intervention group1: Children with vitamin D levels less than 29 ng / ml will be treated with 50,000 units of vitamin D supplement per week for 8 weeks. Vitamin D and IGF-1 levels will be measured again 3 months after starting treatment Control group: In this group, routine care measures are performed and no intervention is performed. Only vitamin D levels and insulin-like growth factor were measured at the beginning and end of the study, and the results were compared with the intervention group. Idiopathic short stracture. Timepoint: Three months. Method of measurement: Vitamin D and IGF-1 levels were measured by blood tests. Esfahan University of Medical Sciences Approved 2017-06-18 Isfahan university of medical sciences Hezarjareeb Isfahan Isfehan Iran (Islamic Republic of)