IRCT201111014877N7 IRCT 2012-08-22 Vice chancellor for research, Dental Faculty of Isfahan University of Medical Sciences Evaluation of efficacy of gel prepared from plants of Quercus Brantii L and Coriandrum Sativum L on periodontal clinical indices. there is no acronym Evaluation of efficacy of topical subgingival application of gel prepared from plants of Quercus Brantii L and Coriandrum Sativum L compared with placebo gel on periodontal clinical indices in moderate chronic periodontitis patients. 2012-02-20 anticipated 35 Complete https://irct.ir/trial/5220 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Single blind study means that the examiner who had the task of gathering information, was unaware of treatment of prescribed for each site. 2 chronic periodontitis. Intervention 1: Ten patients were selected with moderate chronic periodontitis (with 4 or more sites with a probing depth of 3-5 mm). Totally seventy sites (pockets) were selected and divided into experimental and control sites randomly. Clinical indices: Plaque index (PI), Probing pocket depth (PPD), clinical attachment loss (CAL) and Papilla Bleeding Index (PBI) were measured before treatment. Experimental sites were treated with scaling and root planning (SRP) adjunctive topical subgingival application of gel was prepared from plants extract of Quercus Brantii L (20%) and Coriandrum Sativum L (1%) in pharmacy Faculty of Isfahan University of Medical Sciences. Gel was supplied in syringe (0.2 ml) with 21 gauge needle into the pocket. This was done two times. Also clinical indices were measured one and three months after treatment. Intervention 2: Control sites were treated with SRP and topical application of placebo gel into periodontal pockets. It was applied subgingivally using similar syringe and needle as that of experimental gel.