IRCT20200507047344N2 IRCT 2020-12-05 Esfahan University of Medical Sciences The efficacy of plasmapheresis in the treatment of patients poisoned with aluminum phosphide Evaluation of the efficacy of plasmapheresis in comparison with conventional treatment on electrolyte and coagulation parameters in patients poisoned with aluminum phosphide 2020-11-21 anticipated 60 Complete https://irct.ir/trial/52254 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: Considering that in this study, one group of patients will receive the usual treatment and the other group will also undergo plasmapheresis, so the specialist and the patient are aware of the type of intervention, but the person who examines the patient's condition and the data analyst will not be aware of the type of study groups. 2-3 Aluminum phosphide poisoning. Intervention 1: Control group: Patients in this group will receive only routine treatment. Continuous injection of normal saline and dopamine will be done along with olive oil gavage. In addition, intravenous administration of vitamin C at a dose of 150 mg/h, notch (NAC) at a dose of 300 mg/kg in 24 hours, 1 g magnesium sulfate and 1 g calcium gluconate every 6 hours. Vitamin E will also be given intramuscularly at a dose of 300 units every 12 hours. Intervention 2: Intervention group: Patients in this group will undergo plasmapheresis in addition to routine treatment. This treatment will be performed for 3 hours in the first 6 hours of the visit and the patient's plasma will be replaced with an approximate amount of 2 to 3 liters of plasmapheresis. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information