IRCT20131124015510N4 IRCT 2021-06-11 Mazandaran University of Medical Sciences Comparison of quadruple therapy and high dose dual therapy on Helicobacter pylori eradication Comparison of the efficacy of 14- day concomitant regimen with 14- day high dose esomeprazole and amoxicillin regimen on Helicobacter pylori eradication 2020-05-09 anticipated 240 Complete https://irct.ir/trial/52543 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, we use a Random Number Generator to extract 240 random numbers from one to 240. These 240 extracted numbers include 1 and 2, which are arranged randomly and then the first number of patients are included in the study Number 1 receives the standard regimen and number 2 receives the study regimen, Blinding description: Patients who include the the study would be blind. 3 Helicobacter pylori infection. Intervention 1: Control group: Patients receiving the standard 14-day Helicobacter pylori eradication regimen. Intervention 2: Intervention group: Patients receiving 14 days high-dose PPI and amoxicillin regimens for Helicobacter pylori eradication. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is publication after completion of the study