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IRCT20180818040823N1 IRCT 2020-12-19 Tehran University of Medical Sciences The evaluation of the effect of pentoxifylline on diabetic foot ulcers The evaluation of the effect of pentoxifylline on lower extremity blood flow in high-risk diabetic patients for diabetic foot ulcers using muscle perfusion scan byTc99m-MIBI in a pilot study 2019-03-19 anticipated 18 Complete https://irct.ir/trial/52839 observational Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention. 2 Diabetes mellitus. Intervention group: A group of 18 people received 400 mg of pentoxifylline twice daily for 4 - 6 weeks. Imaging of the lower extremities was performed before and after the period of medication administration by gamma camera of ADAC device.. Yes - There is a plan to make this available What will be shared: The sharable data in addition to the quantitative and qualitative analysis performed is before and after medication images which be will be share deidentified. When: The access period will start 6 months after the results are published To whom: Both academics and non-faculty medical staff will be able to use it. Conditions: The deidentified images of the patient will be available to the principal investigator and can be used by people who need access. Where to obtain: Applicants can contact the principal researcher by email for more information and data than published in the form of articles and also before and after taking the medication images. How to obtain: For more information, after sending the e-mail, an initial response will be given up to 24 hours later, and according to the type of applied information, they will be provided to the applicant up to 1 month after the initial e-mail. Comments:
public Dr. Mehrshad Abbasi
Department of Nuclear Medicine, Imam khomeini hospital complex, Qarib Street , Tehran, Iran
Tehran Iran (Islamic Republic of) 1419733141 +98 21 6119 2405 meabbasi@tums.ac.ir Tehran University of Medical Sciences scientific Dr. Mehrshad Abbasi
Department of Nuclear Medicine, Imam khomeini hospital complex, Qarib Street , Tehran, Iran
Tehran Iran (Islamic Republic of) 1419733141 +98 21 6119 2405 meabbasi@tums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Being Diabetic for more than 5 years male patients Candidate for pentoxifylline based on endocrinologist diagnosis no limit no limit Male History of diabetic foot ulcer patient dissatisfaction with enrollment History of macro or microvascular complications of diabetes (proliferative retinopathy, myocardial infarction, stroke, renal failure requiring dialysis) Impossibility of dorsal and plantar flexion of the foot History of any trauma, tumor or other disease in the lower extremities E08 Diabetes mellitus due to underlying condition Prevention Intervention group: A group of 18 people received 400 mg of pentoxifylline twice daily for 4 - 6 weeks. Imaging of the lower extremities was performed before and after the period of medication administration by gamma camera of ADAC device. Increased perfusion reserve of the lower extremities. Timepoint: Imaging was performed at the beginning of the study (before the intervention) and 4 to 6 weeks after taking the Medication. Method of measurement: Gamma camera imaging. Tehran University of Medical Sciences Approved 2019-03-17 Ethics Committee of Tehran university of Medical Science research office, 1st floor, block NO1 of medical science faculty, Poorsina St , Qods St, Enghelab Sq. Tehran Tehran Iran (Islamic Republic of)