IRCT20150913024006N5 IRCT 2021-03-02 Esfahan University of Medical Sciences The effect of adding sertraline to dapoxetine in relieving sexual problems in men Comparative study on the efficacy of add-on sertraline or dapoxetine to PDE-5 inhibitors (phosphodiesterase type 5) on the erectile function and intra-vaginal ejaculation latency time (IELT) among patients with concomitant erectile dysfunction and premature ejaculation 2021-04-03 anticipated 50 Complete https://irct.ir/trial/52939 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: For randomization patients in the two groups simple randomization is used. For this purpose, 50 pieces of paper with the letter A written on 25 of them and the letter B written on the other 25 pieces are poured into the box. Each patient is asked to take a sheet out of the box when entering the study. Depending on what is written on the sheet, the patient enters the first group (A) or the second group (B), Blinding description: This study is performed by two-blind method. Medications in similar packages prepared by the pharmaceutical company are provided by the researcher to patients who are unaware of the contents of the packages. The outcome of treatment is also assessed by another psychiatrist who is unaware of the type of medication the patient is receiving. 3 Erectile dysfunction. Intervention 1: Intervention group 1: This group of patients take a 60 mg oral tablet of dapoxetine made by Exir Pharmaceutical Company one to three hours before the start of sexual activity with the maximum allowed dose for 24 hours. Intervention 2: Intervention group 2: This group takes a 50 mg Sertraline tablet made by Osweh Pharmaceutical Company twice a day for a month. No - There is not a plan to make this available Justification or reason for not sharing IPD is The plan belongs to a government agency and cannot be shared.