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IRCT20201213049704N1 IRCT 2021-04-11 Sanandaj University of Medical Sciences A comparative study on effect of Alpha danan and sensodyne toothpastes on pH salivary chang. A comparative study on effect of Alpha danan and sensodyne toothpastes on pH salivary chang. 2021-05-04 anticipated 40 Complete https://irct.ir/trial/53218 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Crossover, Purpose: Prevention, Randomization description: The names of the people who are eligible to enter the research are written on separate cards and we put them all in a pot, then the people who are pulled out one by one, form the research samples that Simple random forms are divided into groups one and two, for this purpose, according to the number of sample people, we put cards in the pot on which we write the number one and the other half number two, and the people based on their card number in There are one or two groups (depending on the type of study (cross-clinical trial), each person is measured against himself / herself, so there is no need to match the groups in terms of age and gender), Blinding description: Blinding participants: To eliminate bias, we use double-blind, for this purpose, two types of toothpaste are poured into similar white tubes so that it is not possible to identify the type of toothpaste by the samples and the amount of error and Minimize orientation. Outcome Evaluation Blindness: The pH measurement with a pH meter is performed by a research student who has acquired the necessary skills to do so and is unaware of the type of toothpaste used by the samples. 4 Dental caries. Intervention 1: Intervention group: Intervention group: Group I (half of the study volume, which uses alpha toothpaste in the first intervention and toothpaste under the brand name Sensodyne in the second intervention (72 hours later)). Group two (half of the study volume that used toothpaste under the brand name Sensodyne in the first intervention and alpha toothpaste in the second intervention (72 hours later).). Intervention 2: Control group: According to the type of study (crossover clinical trial), each person is measured against himself. In other words, the intervention groups at each stage are their control group for the next intervention. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No discussion has been held with the tutor in this regard yet.
public Mohammad Rastegar Khosravi
Kurdistan University of Medical Sciences, Pasdaran Blvd
Sanandaj Iran (Islamic Republic of) 6617939438 +98 87 3559 1128 bababarbod@gmail.com Sanandaj University of Medical Sciences scientific Mohammad Rastegar Khosravi
Kurdistan University of Medical Sciences, Pasdaran Blvd
Sanadaj Iran (Islamic Republic of) 6617939438 +98 87 3559 1128 bababarbod@gamil.com Sanandaj University of Medical Sciences Iran (Islamic Republic of) Samples are among the students of Sanandaj Dental School. Samples complete the consent form. Be in the age group of 35-18 years. . The specimens do not have systemic diseases that affect saliva, such as diabetes, asthma, kidney and liver failure, epilepsy, blood and glandular disorders. . Samples do not have removable orthodontic appliances and prostheses. Samples have not recently undergone radiotherapy. Samples are not smokers. Samples Do not use antihypertensive drugs and antibiotics regularly. 18 years 35 years Both 1. Samples are allergic to toothpaste compounds. 2. If you do not participate in the second stage of intervention. K02.9 Dental caries, unspecified Other Other Intervention group: Intervention group: Group I (half of the study volume, which uses alpha toothpaste in the first intervention and toothpaste under the brand name Sensodyne in the second intervention (72 hours later)). Group two (half of the study volume that used toothpaste under the brand name Sensodyne in the first intervention and alpha toothpaste in the second intervention (72 hours later).) Control group: According to the type of study (crossover clinical trial), each person is measured against himself. In other words, the intervention groups at each stage are their control group for the next intervention. Saliva pH. Timepoint: In the first intervention: before brushing with toothpaste and after brushing with toothpaste. 72 hours later, perform the second intervention: before brushing with toothpaste and after brushing with toothpaste. Method of measurement: PH meter model pH meter BASIC 20+. Sanandaj University of Medical Sciences Approved 2020-02-16 Ethics committee of kurdestan University of Medical Sciences Kurdistan Besat Medical Sciences Dormitory, Above Jam Jam Crossroads, Adab Street Sanandaj Kurdistan Iran (Islamic Republic of)