IRCT20200929048876N3 IRCT 2021-01-08 Zanjan University of Medical Sciences Diet and intestinal microbiota alterations Assessment and comparison of the effects of two types of low calorie low carbohydrate and low fat diets on intestinal microbiota changes and its association with some of metabolic factors alterations in obese women 2021-01-09 anticipated 40 Complete https://irct.ir/trial/53223 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Prevention, Randomization description: Blocked randomization will be used as two groups with 4-number blocks including 5 participant in each group. randomization unit is person and we will use random allocation software for this purpose. random coded boxes will be used for concealment. At this method, cans with similar weight, shape and color which are numbered according to the random sequence will be used. N/A Obesity. Intervention 1: Intervention and control group: From the total daily calorie needs, 500 kcal per day will be reduce for 0.5 kg weight reduction in each patient. In low fat diet 20% of total daily calorie will receive from fat (with emphasis on mono and poly- unsaturated plant fatty acids), 15% from protein and 65% from carbohydrates. Intervention 2: Control and intervention group: From the total daily calorie needs, 500 kcal per day will be reduce for 0.5 kg weight reduction in each patient. In low carbohydrate diet 20% of total daily calorie will receive from carbohydrate, 25% from protein and 55% from fats (with emphasis on mono and poly- unsaturated plant fatty acids). Yes - There is a plan to make this available What will be shared: without participant name When: After study final To whom: All person Conditions: All person Where to obtain: Zanjan University of Medical Sciences, Deputy of Research and Thechnology How to obtain: straight referee to Deputy of Research and Technology of Zanjan University of Medical Sciences Comments: