IRCT20100102002963N30 IRCT 2021-04-24 Azad Islamic University Of Yazd Comparison of the effect of intravenous labetalol administration with intravenous lidocaine on hemodynamic variables and postoperative nausea and vomiting Comparison of the effect of intravenous labetalol administration with intravenous lidocaine on hemodynamic variables during laryngoscopy and endotracheal intubation and postoperative nausea and vomiting in female patients undergoing abdominal surgery 2021-05-10 anticipated 64 Complete https://irct.ir/trial/53321 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In order to randomly allocate 64 eligible applicants, we randomly divide them into two groups of 32 people. For this purpose, we use Random allocation software version 1.0 under Windows to create a sequence, and by using this software we make A list which is specified from 1 to 64 with group A or B treatment By Using this list, we give the first person who is eligible to enter the study, number one and the last person the number 64, then based on the random allocation list and by the software, it is determined which group A or B each person is in, Blinding description: This study is a single-blind randomized clinical trial in which patients are unaware of the type of drug being prescribed, so that the two drugs are prepared and coded in two identical syringes. And according to random numbers, the specified code is given to the patients. 2-3 Comparison of the effect of intravenous labetalol with intravenous lidocaine on hemodynamic variables during laryngoscopy and endotracheal intubation and postoperative nausea and vomiting in patients undergoing abdominal surgery. Intervention 1: Intervention group1: In this group, 10 mg of labetalol, from Kern pharma company is injected intravenously and once immediately before induction of general anesthesia to eligible patients. Intervention 2: Intervention group2: In this group, lidocaine 1.5 mg per kg body weight of the patient, from Caspian tamin company is injected intravenously and once immediately before induction of general anesthesia to eligible patients. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is no more information