IRCT20120817010617N7 IRCT 2021-05-20 Zahedan University of Medical Sciences Efficacy of brimonidine & latanoprost in treatment normal tension glaucoma Assessment of efficacy of brimonidine versus latanoprost for visual improvement in normal tension glaucoma patients 2021-03-10 anticipated 100 Complete https://irct.ir/trial/53473 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients were randomly assigned to intervention group A and B using randomized block design with block size 6. Randomization was done using online random allocation software, Blinding description: In this single-blind study, only patients are blinded to the content of drug A or B. The examiner, optometrist and secretary of clinic are completely informed of the contents of type A and B drugs. 2-3 Normal Tension Glaucoma. Intervention 1: Intervention group1: Prescription of eyedrop Brimonidine 0.2% made in Iranian Sina daroo inc, every 12 hours in the eye. Intervention 2: Intervention group 2: Prescription of Eyedrop latanoprost 0.005% made in Iranian Sina daroo inc. once daily at 9 PM in the eye. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.