IRCT20201204049599N1 IRCT 2021-02-13 Oroumia University of Medical Sciences Effect of gluten free diet on irritable bowel syndrome symptoms Comparison of the effect of gluten free diet and regular diet on severity of clinical symptoms in patients with irritable bowel syndrome 2020-01-21 anticipated 44 Complete https://irct.ir/trial/53506 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method is simple randomization. the researcher will divide patients by using table of random numbers. First, each patient will be assigned a two-digit code according to the date and time of the clinic visit. The first patient will have code 01 and the last patient will have code 44. Then in the table of random numbers without looking, a location will be randomly selected. The first two digits will be examined. If the number is less than or equal to 44, it will be selected, otherwise we will continue moving in the direction of the line and other numbers will be checked. If it is a duplicate number, it will be ignored and another number from the table will be checked. We continue this process until 22 codes are selected. The first 22 codes will be for patients in the intervention group (patients who will receive a gluten-free diet) and the remaining 22 codes will be for the control group (patients who will receive a normal diet). Thus, patients are randomly divided into two groups. N/A Irritable Bowel Syndrome. Intervention 1: Intervention group: Gluten free group. in this group necessary education about gluten free diet and foods that patients must avoid including wheat, barley and rye will be provided. At the beginning demographic information and symptoms will be documented. after 4 weeks patients will be reevaluated. Intervention 2: Control group: Normal Diet group. This group of patients will continue their normal diet with out any further intervention At the beginning demographic information and symptoms will be documented. after 4 weeks patients will be reevaluated. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information provided.