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IRCT20210122050109N1 IRCT 2021-02-28 Qazvin University of Medical Sciences The effect of dexamethasone on postoperative hand fracture pain Determination of the effect of intravenous dexamethasone during anesthesia and analgesia of axillary block in upper limb fracture surgery 2021-02-19 anticipated 25 Complete https://irct.ir/trial/53928 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple random: In this method, first the list of names of all patients will be obtained, then a number will be assigned to each of them and the required number will be selected using a table of random numbers, Blinding description: In this study, the patient will not be aware of the type of study group in which he is placed, as well as the researcher, patient surgeon, patient care nurse in the operating room, recovery ward and post-surgery ward, as well as data analyzer will not be informed about patient grouping. 2-3 Fracture of forearm. Intervention 1: Intervention group: The intervention group will receive 8 mg dexamethasone intravenously in the relevant box and then 0.02 mg / kg midazolam and 2 micrograms / kg fentanyl will be injected intravenously. Then, while the patient is in the supine and arm position in the 90-degree abduction position and the elbow is in the 90-degree flexion position, after filling the position with alcohol and betadine and numbing the skin and subcutaneous tissue with 2 cc of 1% lidocaine by 25G needle, with ultrasound guide and linear probe that is transversely located at the intersection of pectoral and biceps muscles in the proximal inner part of the arm Guide around the arteries seen hypercoa and around each nerve 10 cc of the contents of the 20 cc syringes in the box of the same group will be slowly injected (median nerve in the upper and inner part of the artery and ulnar nerve in the part Upper and external artery and radial nerve in the lower part of the artery). Intervention 2: Control group: The control group will receive 2 cc of normal saline (placebo) in the box instead of dexamethasone. Yes - There is a plan to make this available What will be shared: Data on primary and secondary outcomes can be published. When: One year after the results are published To whom: Researchers and industry owners Conditions: Use the results for further planning and research Where to obtain: Alizadeh25@yahoo.com How to obtain: Alizadeh25@yahoo.com Comments:
public Anahita Janbaz
Rajaei Hospital, Padegan St., Qazvin, Iran
Qazvin Iran (Islamic Republic of) 3419759811 +98 28 3333 5800 anahita.j201@gmail.com Qazvin University of Medical Sciences scientific Dr. Ali Alizadeh Oujvar
Qazvin University of Medical Sciences, Bahonar Blvd, Qazvin, Iran.
Qazvin Iran (Islamic Republic of) 3419759811 +98 28 3336 9001 Alizadeh25@yahoo.com Qazvin University of Medical Sciences Iran (Islamic Republic of) All patients candidates for axillary block surgery for upper limb surgery (forearm and hand) due to bone fractures that require plaque patients in the age range of 20 to 60 years 20 years 60 years Both Level of consciousness disorder (GCS <15) drug or alcohol use history of MAOI, TCA, SSRI, phenothiazines or hypnotics chronic pain based on history and clinical examination history of drug sensitivity Dexamethasone and lidocaine shoulder joint osteoarthritis history of uncontrolled diabetes psychotic disease block failure S52 Fracture of forearm Treatment - Drugs Placebo Intervention group: The intervention group will receive 8 mg dexamethasone intravenously in the relevant box and then 0.02 mg / kg midazolam and 2 micrograms / kg fentanyl will be injected intravenously. Then, while the patient is in the supine and arm position in the 90-degree abduction position and the elbow is in the 90-degree flexion position, after filling the position with alcohol and betadine and numbing the skin and subcutaneous tissue with 2 cc of 1% lidocaine by 25G needle, with ultrasound guide and linear probe that is transversely located at the intersection of pectoral and biceps muscles in the proximal inner part of the arm Guide around the arteries seen hypercoa and around each nerve 10 cc of the contents of the 20 cc syringes in the box of the same group will be slowly injected (median nerve in the upper and inner part of the artery and ulnar nerve in the part Upper and external artery and radial nerve in the lower part of the artery). Control group: The control group will receive 2 cc of normal saline (placebo) in the box instead of dexamethasone. Post operational Pain. Timepoint: Recovery and 1, 2, 4, 6, 12 and 24 hours after receiving the drug. Method of measurement: Numerical Pain Rating Scale. Amount of narcotic drug consumption. Timepoint: Post operation. Method of measurement: Patient Document. Qazvin University of Medical Sciences Approved 2020-02-19 Ethics Committee of Qazvin University of Medical Sciences Qazvin University of Medical Sciences, Bahonar Blvd, Qazvin, Iran Qazvin Qazvin Iran (Islamic Republic of)