]>
IRCT20170417033489N9 IRCT 2021-11-03 Mashhad University of Medical Sciences Evaluation of the synergistic effect of curcumin in controlling urinary irritation symptoms after endoscopic benign prostatic hyperplasia in comparison with anticholinergic treatment alone Evaluation of the synergistic effect of curcumin in controlling urinary irritation symptoms after endoscopic benign prostatic hyperplasia in comparison with anticholinergic treatment alone 2020-11-21 anticipated 80 Complete https://irct.ir/trial/54243 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization; after each patient with the inclusion criteria is referred, an envelope is taken in order and according to the code written in it (for example, group A / group B), the patient enters each of the mentioned groups, Blinding description: One side is blind. Patient. 3 Benign prostatic hyperplasia. Intervention 1: Intervention group: They are treated with anticholinergics at a dose of one tablet twice a day and oral curcumin tablets once a day. After one month from the start of treatment, the results of improving irritative symptoms using the Persian version of the questionnaire (IPSS) again. Will be evaluated. Intervention 2: Control group: Patients are treated with anticholinergics and with the same prescription as the intervention group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I have not decided yet
public Salman Soltani
Department of Urology, on the edge of Imam Reza Square, Ibne Sina Blvd, Mashhad.
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3858 3885 soltanis@mums.ac.ir Mashhad University of Medical Sciences scientific Salman Soltani
Emam Reza hospital, on the edge of Imam Reza Square, Ibn Sina St, Mashhad
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3858 3885 soltanis@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Patients with benign prostatic hyperplasia who have undergone endoscopic surgery and now have symptoms of urinary irritation. 60 years no limit Male Patients with severe preoperative irritation symptoms Existence of fever and symptoms of prostatitis Existence of bladder injury during surgery Existence of active urinary tract infection Having underlying diseases such as high blood pressure Glaucoma D29.1 hyperplasia of prostate (adenomatous) Treatment - Drugs Treatment - Drugs Intervention group: They are treated with anticholinergics at a dose of one tablet twice a day and oral curcumin tablets once a day. After one month from the start of treatment, the results of improving irritative symptoms using the Persian version of the questionnaire (IPSS) again. Will be evaluated. Control group: Patients are treated with anticholinergics and with the same prescription as the intervention group. Score obtained based on the patient's irritating symptoms questionnaire. Timepoint: Before the intervention and one month after taking curcumin. Method of measurement: International Prostate Symptom Score (IPSS). Mashhad University of Medical Sciences Approved 2021-01-20 Mashhad Ethics Committee of the Medical School Department of Knowledge & Health, Shahid Fakouri blvd, Mashhad, Khorasan Razavi Mashhad Mashhad Razavi Khorasan Iran (Islamic Republic of)