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IRCT20210222050455N1 IRCT 2021-04-22 Arak University of Medical Sciences Effects of Arctium Lappa root in individuals with type 2 diabetes Effects of Arctium Lappa root on values of blood sugar, amylase, antioxidants, lipid ratios and insulin resistance in individuals with type 2 diabetes 2021-04-04 anticipated 80 Complete https://irct.ir/trial/54674 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants, healthcare providers and outcome assessors are blinded, Blinding description: Participants, healthcare providers and outcome assessors are blinded.The drug and placebo are packaged in similar packages. The treatment group and placebo group will not be aware of the type of intervention they receive. The statistician will not be informed about the grouping done. 2-3 type 2 diabetes. Intervention 1: Intervention group: One capsule Arctium Lappa root (460 mg) per day for 12 weeks. Intervention 2: Control group: One capsule placebo charcoal (460 mg) day for 12 weeks. Yes - There is a plan to make this available What will be shared: Only results of main outcomes When: Six months after publishing of the results To whom: Only for academic staffs and universities researches Conditions: Only for international and between universities researches Where to obtain: Ali Khosrowbeygi a.khosrowbeygi@arakmu.ac.ir How to obtain: 1. Requesting a team work clinical trial via email. 2. Approving the proposal. 3. Registration of the trial Comments: No comments
public Masoume Ghorbani
Arak University of Medical Sciences,School of Medicine, , Department of Biochemistry,Basij Square,Sardasht,Arak
Arak Iran (Islamic Republic of) 3848176941 +98 86 3417 3501 M.ghorbani7133@gmail.com Arak University of Medical Sciences scientific Masoumre Ghorbani
Arak University of Medical Sciences,School of Medicine, , Department of Biochemistry,Basij Square,Sardasht,Arak
Arak Iran (Islamic Republic of) 3848176941 +98 86 3417 3501 M.ghorbani7133@gmail.com Arak University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Diagnosis of type 2 diabetes over two years (FBS>125 ، 2hpp>200 و HbA1c>6/5 ) No change in the dose of oral blood glucose lowering during testing Maintain physical activity and diet as usual during the test No liver, gastrointestinal and kidney diseases Lack of treatment with anticoagulants Do not take anti hypertensive drugs and diuretics No alcohol No smoking No allergies 40 years 65 years Both People who receive vitamin supplements during the last three months People treated with insulin and other hormones People who are pregnant and breastfeeding E08 Diabetes mellitus due to underlying condition Treatment - Drugs Placebo Intervention group: One capsule Arctium Lappa root (460 mg) per day for 12 weeks Control group: One capsule placebo charcoal (460 mg) day for 12 weeks. Fasting glucose. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric. Amylase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Spectrophotometry. Catalase. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Spectrophotometry. MDA. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Calorimetry. Total antioxidant capacity (TAC). Timepoint: Before and after 12 weeks of intervention. Method of measurement: Calorimetry. Insulin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Eliza. HbA1C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Calorimetry. Lipid profile. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Calorimetry. Lipid ratios(Total Cholesterol/HDl-c and LDL-c/HDl-c). Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula. HOMA-B. Timepoint: Before and after 12 weeks of intervention. Method of measurement: HOMA-IR model evaluation. Body mass index (BMI). Timepoint: Before and after 12 weeks of intervention. Method of measurement: weight/height. Arak University of Medical Sciences Approved 2021-01-24 Ethics committee of Arak University of Medical Sciences Arak University of Medical Sciences,Basij square,Sardasht,Arak Arak Markazi Iran (Islamic Republic of)