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IRCT20180714040460N8 IRCT 2021-04-10 Islamic Azad University The effect of curcumin mouthwash on the indicators of gingivitis and dental plaque The effect of curcumin mouthwash on the indicators of gingivitis and dental plaque in patients referred to the School of Dentistry 2021-04-10 anticipated 51 Complete https://irct.ir/trial/54722 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, patients with generalized gingivitis are selected and included in the study. Patients are randomized in a block, so that packages consisting of 9 papers consisting of 3 papers from each group (3 to chlorhexidine, 3 to curcumin and 3 to control) are placed in front of the patient and the patient selects one of them randomly and enters that group, and after the completion of these 9 patients, the next patients (next 9 people) enter the study so that the process of getting sick can proceed simultaneously in all 3 groups. Next, the process of scaling and reviewing the indicators is done by a trained person who does not know what group the patient is in, so as not to be biased, Blinding description: Clinical caregivers and outcome assessors have no idea which groups the participants will be studied in. 2-3 Gingival inflammation and dental plaque. Intervention 1: Control group: Patients who do not use any mouthwash and the desired indicators (plaque and gingivitis) are measured on the first day and then scaling and after 14 days the indicators are checked again. Intervention 2: First intervention group: Patients who are initially scaled and after measuring the indicators for 14 days use Najo chlorhexidine mouthwash for 0.2% and the indicators are evaluated 14 more times a day. People who are going to use mouthwash are told to use 10 ml of mouthwash twice a day for 30 minutes after brushing for 30 seconds and do not eat anything for 30 minutes after using the mouthwash. Intervention 3: Second Intervention group : Patients who are initially scaled and after measuring the indicators for 14 days use curcumin mouthwash 0.2% of Sina Curcumin company and the indicators are evaluated 14 times a day. People who are going to use mouthwash are told to use 10 ml of mouthwash twice a day for 30 minutes after brushing for 30 seconds and do not eat anything for 30 minutes after using the mouthwash. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Seyed Navid Mirazimi
No 1, Fifth Narenjestan Ave, Pasdaran Ave
Tehran Iran (Islamic Republic of) 1957917711 +98 21 2282 6301 navidmirazimi@gmail.com Islamic Azad University scientific Dr. Nima Naddafpour
Neyestan 9 Ave, Pasdaran Ave
Tehran Iran (Islamic Republic of) 1946853314 +98 21 2256 4570 nima.na04@gmail.com Islamic Azad University Iran (Islamic Republic of) 20>Age>40 Dental plaque Bleeding on probing>10% Gingivitis 20 years 40 years Both Pregnant women People who have had periodontal treatment in the last 6 months History of curcumin sensitivity Tobacco consumers Patients treated with systemic antibiotics K05 Gingivitis and periodontal diseases Treatment - Other Treatment - Other Treatment - Other Control group: Patients who do not use any mouthwash and the desired indicators (plaque and gingivitis) are measured on the first day and then scaling and after 14 days the indicators are checked again. First intervention group: Patients who are initially scaled and after measuring the indicators for 14 days use Najo chlorhexidine mouthwash for 0.2% and the indicators are evaluated 14 more times a day. People who are going to use mouthwash are told to use 10 ml of mouthwash twice a day for 30 minutes after brushing for 30 seconds and do not eat anything for 30 minutes after using the mouthwash. Second Intervention group : Patients who are initially scaled and after measuring the indicators for 14 days use curcumin mouthwash 0.2% of Sina Curcumin company and the indicators are evaluated 14 times a day. People who are going to use mouthwash are told to use 10 ml of mouthwash twice a day for 30 minutes after brushing for 30 seconds and do not eat anything for 30 minutes after using the mouthwash. Dental plaque: Determining the amount of dental plaque is evaluated based on the TURESKY index and is measured after using the disclosure pill and is expressed between 0-5 according to the presence or absence of plaque. Gingivitis: Based on the bleeding areas and based on the Modified Sulcular bleeding index is measured with a periodontal probe and is expressed between 0-3 depending on the presence or absence of bleeding. Timepoint: Day 0 and day 14. Method of measurement: Dental plaque: Determining the amount of dental plaque is evaluated based on the TURESKY index and is measured after using the disclosure pill and is expressed between 0-5 according to the presence or absence of plaque. Gingivitis: Based on the bleeding areas and based on the Modified Sulcular bleeding index is measured with a periodontal probe and is expressed between 0-3 depending on the presence or absence of bleeding. Islamic Azad University Approved 2021-01-08 Ethics Committee of Tehran Azad University of Medical Sciences Neyestan 9 Ave, Pasdaran Ave Tehran Tehran Iran (Islamic Republic of)