]>
IRCT20200217046523N12 IRCT 2021-03-09 Esfahan University of Medical Sciences Remifentanil and control bleeding during lumbar fusion surgery Comparative study of the effect of two different doses of remifentanil on bleeding control in lumbar fusion surgery under general anesthesia 2021-04-20 anticipated 110 Complete https://irct.ir/trial/54856 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization, table of random numbers. In this study, reading the table of predefined random numbers (eg, up or down) and the researcher's second default is to consider even numbers for intervention group . The researcher begins to read the numbers in a predetermined manner and the patients are divided. 2-3 Spinal fusion surgery. Intervention 1: Intervention group 1: Patients in this group undergo vertebral fusion surgery under general anesthesia and receive remifentanil at a dose of 0.1 μg / kg. Patients' blood pressure and bleeding during surgery and recovery will be measured every 30 minutes. Intervention 2: Intervention group 2: Patients in this group undergo vertebral fusion surgery under general anesthesia and receive remifentanil at a dose of 0.3 μg / kg. Patients' blood pressure and bleeding during surgery and recovery will be measured every 30 minutes. Yes - There is a plan to make this available What will be shared: All data can be shared after people have requested. When: Six months after publishing the results. To whom: Academic researchers Conditions: Scientific uses Where to obtain: Isfahan University of Medical Sciences website How to obtain: Clear request on the site to access the data by the individual and then review the request by the research assistant within 2 weeks and then allow access to the data. Comments:
public Mehrdad Masoudifar
No. 22, Roshd Ave., Daneshgah Blvd., Isfahan
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3337 7986 masoudifar@med.mui.ac.ir Esfahan University of Medical Sciences scientific Mehrdad Masoudifar
No. 22, Roshd Ave., Daneshgah Blvd., Isfahan
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3337 7986 masoudifar@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) Patient consent to participate in the study Patient candidate for posterior spinal fusion surgery at levels 1 and 2 Not taking antihypertensive drugs 18 years 70 years Both Changing the technique of operation and anesthesia for various reasons Unwanted hemodynamic complications due to surgical technique Severe cardiovascular disease H53.32 Fusion with defective stereopsis Treatment - Drugs Treatment - Drugs Intervention group 1: Patients in this group undergo vertebral fusion surgery under general anesthesia and receive remifentanil at a dose of 0.1 μg / kg. Patients' blood pressure and bleeding during surgery and recovery will be measured every 30 minutes. Intervention group 2: Patients in this group undergo vertebral fusion surgery under general anesthesia and receive remifentanil at a dose of 0.3 μg / kg. Patients' blood pressure and bleeding during surgery and recovery will be measured every 30 minutes. Blood pressure. Timepoint: Every 30 minutes during surgery and recovery. Method of measurement: Measured by the device. Bleeding. Timepoint: Every 30 minutes during surgery and recovery. Method of measurement: Count the number of gases. Esfahan University of Medical Sciences Approved 2021-02-06 Ethics committee of IsfahanUniversity of Medical Sciences Isfahan University of Medical Sciences, Hezar Jarib Ave., Isfahan Isfahan Isfehan Iran (Islamic Republic of)