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IRCT201011095144N1 IRCT 2011-01-28 Nutririon research center Effect of ω-3 fatty acids on gastric cancer patients Study on the effect of ω-3 fatty acids supplementation on nutritional status, some inflammatory factors and matrix metalloproteinases in gastric cancer patients undergoing chemotherapy 2010-05-22 anticipated 30 Complete https://irct.ir/trial/5491 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 Gastric cancer patients undergoing chemotherapy. Intervention 1: Interventions 1: ω-3 fatty acids, 3 g daily for 45 days. Intervention 2: interventions2: rice powder, three capsules daily for 45 days.
public
scientific Ali Nemati
Basic Science group, Faculty of Medicine, Ardebil University of Medical Sciences
Ardebil Iran (Islamic Republic of) Iran +98 45 1551 0052 a.nemati@arums.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients with gastric cancer in phase 3 (cardia and non cardia) during chemotherapy over 30 years old. Exclusion criteria: other diseases induced cachexia such as heart disease, lung, AIDS, renal disease, incidence of acute leukemia, diabetes and multiple myeloma, individauls undergoing surgery and who do not take the given drugs properly during the study period. 30 years 100 years Both C16 Malignant neoplasm of stomach Treatment - Drugs Placebo Interventions 1: ω-3 fatty acids, 3 g daily for 45 days interventions2: rice powder, three capsules daily for 45 days Weight. Timepoint: days of 0, 30 and 45. Method of measurement: digital scale. Body Mass Index. Timepoint: days of 0, 30 and 45. Method of measurement: measured by ratio of weight (kilograms) to squared height (m). Daily calorie intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire. Daily nutreints intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire. Nausea. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire. Vomiting. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire. Appetite. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire. Dairreha. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnare. Abdominal cramp. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire. Total antioxidant. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry. MDA. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry. Interleukin1. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Interleukin 6. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Interleukin 2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. TNF-ɑ. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Mmp9. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Mmp2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Cholestrol. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. Triglyceride. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. TIBC. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. Blood albumin. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. LDL- C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. HDL-C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. Blood iron. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. CRP. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. Proxonaz 1. Timepoint: days of 0, 30 and 45. Method of measurement: spectophotometry. IgA. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. IgG. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. IgM. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA. Transferrin. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer. Nutririon research center Approved 2010-12-01 Vice Chancellor of Research in Tabrizl University of medical sciences Vice Chancellor of Research, Tabriz University of medical sciences, Daneshgah St. Tabriz Iran (Islamic Republic of)