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IRCT20160516027929N9 IRCT 2021-03-19 Shahid Beheshti University of Medical Sciences Evaluation of the effect of HFNC use in COPD patients Evaluation of the effect of using high flow oxygen delivery through nasal cannula (HFNC) with different currents, in improving the respiratory symptoms of patients with chronic obstructive pulmonary disease (COPD) referred to Masih Daneshvari Hospital 2021-03-21 anticipated 30 Complete https://irct.ir/trial/54924 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method: Simple randomization. Randomization unit: individual. Randomization tool: Random number table. Patients are divided into 3 groups treated with different flows of 30, 40, and 60 liters per minute based on the codes assigned to each patient (using file number), Blinding description: To prevent any possible complications, the primary caregiver is aware of the allocation of treatment groups. Patients in the study were also not blinded to the treatment they were receiving. Researchers responsible for data collection and analysis are not aware of the allocation of different study groups. 2 Chronic obstructive pulmonary disease. Intervention 1: First intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 30. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. Intervention 2: Second intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 40. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. Intervention 3: Third intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 60. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information.
public Atefeh Fakharian
Masih Daneshvari Hospital, Darabad
Tehran Iran (Islamic Republic of) 1956944413 +98 21 2610 5050 fakharian_2005@yahoo.com Shahid Beheshti University of Medical Sciences scientific Atefeh Fakharian
Masih Daneshvari Hospital, Darabad
Tehran Iran (Islamic Republic of) 1956944413c +98 21 2610 5050 fakharian_2005@yahoo.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Signing a written consent form No intubation Hypoxemic respiratory distress 18 years no limit Both PaCO2> 65 pH < 7.28 Age less than 18 years Cardiovascular disorders that prevent respiratory rehabilitation Diagnosis of medical staff based on the patient's absence from participating in this study J44 chronic obstructive pulmonary disease Treatment - Devices Treatment - Devices Treatment - Devices First intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 30. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. Second intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 40. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. Third intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 60. The inlet air temperature is set to 34 ° C to ensure proper humidity to the patient's inhaled air. Forced expiratory volume in first second. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry. Oxygen saturation. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Pulse oximetry. Forced vital capacity. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry. Partial pressure of carbon dioxide. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: VBG analysis. Borg scale. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Questionnaire review. CAT score. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Questionnaire review. Shahid Beheshti University of Medical Sciences Approved 2021-03-08 Ethics Committee of Shahid Beheshti University of Medical Sciences Dr. Masih Daneshvari Hospital, Darabad, Shahid Bahonar St. (Niavaran) Tehran Tehran Iran (Islamic Republic of)