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IRCT20210323050758N1 IRCT 2021-04-04 Rasht University of Medical Sciences Effect of L-Citrulline after high-intensity interval exercise Effects of L-citrulline supplementation on nitric oxide and antioxidant markers after high-intensity interval exercise in humans: a randomized controlled trial 2018-12-06 anticipated 12 Complete https://irct.ir/trial/55192 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Basic scienece, Randomization description: By using the lottery method, we prepare 9 sheets numbered 1to 9 that the even numbers belong to the control group and the odd numbers belong to the supplement group. Then, the lottery is done by participants. Randomization is determined by the researcher's assistant in the form of a double-blind design. Due to the crossover study, the study participants will be switched throughout to the second groups (supplement or placebo) after a washout period, Blinding description: Both the researcher and participants did not know if participants were receiving the supplement or a placebo in the training sessions. N/A Evaluation of antioxidant markers. Intervention group: participants consume a solution of 12g of l-citrulline powder supplementation with water 1 to 2 hours before the start of the exercise. Control group: participants consume a solution of 12g of maltodextrin powder with water 1 to 2 hours before the start of the exercise.. Yes - There is a plan to make this available What will be shared: After the study, information about the main outcome will be shared. When: 6 months after publication To whom: Scientific researchers Conditions: Data and results will be available for research on L-citrulline. Where to obtain: Javad Mehrabani mehrabanij@guilan.ac.ir 0098 9112309074 How to obtain: The data will be provided to the applicant within one month after review and approval. Comments:
public Kosar Valaei
No. 14, Farhang Ave., Talebamoli Blvd., Amol Town
Amol Iran (Islamic Republic of) 4615973556 +98 11 4428 9094 kosar.valaei94@gmail.com Rasht University of Medical Sciences scientific Kosar Valaei
No. 14, Farhang Ave., Talebamoli Blvd., Amol Town
Amol Iran (Islamic Republic of) 4615973556 +98 11 4428 9094 kosar.valaei94@gmail.com Rasht University of Medical Sciences Iran (Islamic Republic of) All healthy, trained male students at the University of Guilan 20 years 23 years Male Being disease and injury free No history of surgery and musculoskeletal disorder during the last two years No history of ergogenic aids, supplements and drug use for in the last 6 months leading to the study Placebo Intervention group: participants consume a solution of 12g of l-citrulline powder supplementation with water 1 to 2 hours before the start of the exercise. Control group: participants consume a solution of 12g of maltodextrin powder with water 1 to 2 hours before the start of the exercise. Nitric Oxide, Superoxide dismutase, Catalase, Glutathione peroxidase. Timepoint: Before exercise, immediately after , post 10, and post 30 after exercise. Method of measurement: Blood sampling. Rasht University of Medical Sciences Approved 2019-02-04 Ethics committee of Guilan University of Medical Science No. 14, Farhang Ave., Talebamoli Blvd., Amol Town Amol Mazandaran Iran (Islamic Republic of)