IRCT20210306050604N1 IRCT 2021-06-29 Yazd University of Medical Sciences Evaluation of the effect of tissue adhesive and suture on the postoperative pain Evaluation of the effect of tissue adhesive and suture techniques on the postoperative pain after the tooth extraction 2021-04-12 anticipated 18 Complete https://irct.ir/trial/55586 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Randomization description: In this study, 18 qualified patients will be selected. For each patient, the first premolars will be extracted in the first session and the first premolars on the opposite side of the same jaw will be extracted in the second session and additionally the wound will be covered with sutures or mucosal adhesive. All the patients will be numbered (1 to 18). First, using Random allocation software version 1 and block random allocation method, we will determine the random sequence for numbers 1 to 18. For each number, either the mucosal adhesive (A) or sutures (B) interventions will be applied either in the first turn or in the second turn. Totally, 18 pair blocks (an A&B pair block for each patient) will be identified. In order to blind the random allocation, the random allocation list will be given a third party who knows nothing about the interventions and will be asked on the phone to choose intervention A or B for the patient, Blinding description: In order to blind the study in both directions, the patient and the statistical consultant will not know which side of the tooth is pulled at each stage and which technique is used to cover the wound. N/A Evaluation of the effect of tissue adhesive and suture techniques on the postoperative pain after the tooth extraction. Intervention 1: First Intervention group: After injection of Lidocaine 2% 1.100000(Darou Pakhsh- Iran), one of premolars on the left or right side will be extracted by a surgical resident and it will be sutured using Supasil (3.0 silk thread made in Supa Medical Devices) according to figure eight. Intervention 2: Intervention group 2 will attend the school again after two weeks and their first premolar on the other side will be extracted by the resident and the silent tooth will be covered with mucous adhesive. To use mucosal adhesive, first disinfect the wound with normal saline and select the ora-aid mucous adhesive (TBM company, made in South Korea) in the appropriate size. Then dry the wound area with a wet swab, put the adhesive on the silent tooth and press it for 5 to 10 seconds to stick to the wound. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After the final conclusion, the decision is made about the publication of the data.