IRCT20201015049033N1 IRCT 2021-05-12 Esfahan University of Medical Sciences measuring The effect of tranexamic acid injection during anterior cruciate ligament reconstruction surgery measuring The effect of tranexamic acid injection during anterior cruciate ligament reconstruction surgery on postoperative bleeding, pain and swelling 2021-09-23 anticipated 60 Complete https://irct.ir/trial/55745 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Simple and individual randomization method is done through a random numbers table and The group of patients is given to the operating room nurse to prepare the medicine or placebo for injection. First we defined the framework of our statistical community and randomly started from a point in the table in the direction of the row or column. Depending on the type of code, we selected the same number of digits in the row or column direction. We continued this work until the number of samples was completed. even numbers were used for the intervention group and individual numbers for the control group, Blinding description: The patients has no knowledge of injecting medication or placebo during surgery.A person who monitors the amount of drainage, the degree of hemarthrosis, the range of motion of the knee joint, and the amount of pain and swelling has no knowledge of injecting medication or placebo during surgery. 3 Anterior cruciate ligament rupture. Intervention 1: Intervention group:During anterior cruciate ligament repair surgery, 15 mg / kg tranexamic acid into 100 cc of normal saline is injected before opening the tourniquet. Intervention 2: Control group: During anterior cruciate ligament surgery in the control group with the same volume as the intervention group, normal saline is injected before opening the tourniquet. Yes - There is a plan to make this available What will be shared: Patient information including patient age and preoperative findings and postoperative outcomes that are relevant to the study and the type of drug injected into the patient can be disseminated. When: Six months after the results were published To whom: The data will be available only to researchers working in academic and scientific institutions. Conditions: Data are provided for similar studies and other statistical analyzes. Where to obtain: To receive information, send an email to the following address: drreza.ent@gmail.com How to obtain: About two months after the email is sent and the data is verified. Comments: