]>
IRCT20210427051102N1 IRCT 2021-05-16 Fasa University of Medical Sciences Comparison of the effects of Topiramate and Gabapentin in Opioid withdrawal syndrome Comparison of the effects of Topiramate and Gabapentin in Opioid withdrawal syndrome 2021-06-22 anticipated 60 Complete https://irct.ir/trial/55931 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: We put 60 cards in the envelope, 30 of which are written with gabapentin and the other 30 with topiramate and we ask the patient to choose one of the cards, and the selected card shows which group the patient belongs to. . 3 Opioid Withdrawal syndrome. Intervention 1: Patients in the first group take 300-1200mg of oral Gabapentin daily from Poursina company for one to a maximum of three weeks. Intervention 2: Patients in the second group take 100-300 mg of topiramate daily from Sobhan Daru Company for one to a maximum of three weeks. Yes - There is a plan to make this available What will be shared: All personal data of study participants can be shared after identifying individuals. When: The beginning of the access period from 1401 To whom: researchers and people working in medical universities of the country Conditions: For research purposes and in collaboration with Fasa University of Medical Sciences Where to obtain: Dr. Mojtaba Farjam Faculty Member of Fasa University of Medical Sciences How to obtain: Contact with Dr. Mojtaba Farjam, the project manager via email : farjam.md@gmail.com Comments:
public Parmida Rajabi
Ibn Sina Square, Fasa univercity of medical sciences
Fasa Iran (Islamic Republic of) 7461686688 +98 71 5333 2326 p.rajabi75@gmail.com Fasa University of Medical Sciences scientific Dr.Bahare Fakhraei
Ibn Sina Square, Vali Asr Hospital, Medical doctor building, block 3
Fasa Iran (Islamic Republic of) 7461747377 +98 71 5331 5749 b.fakhraee@gmail.com Fasa University of Medical Sciences Iran (Islamic Republic of) Detection of opioid dependence according to DSM-V criteria 18 years 65 years Both Major medical diseases including cardiovascular, pulmonary, renal and gastrointestinal disorders Pregnancy and Lactation period F11.23 Opioid dependence with withdrawal Treatment - Drugs Treatment - Drugs Patients in the first group take 300-1200mg of oral Gabapentin daily from Poursina company for one to a maximum of three weeks. Patients in the second group take 100-300 mg of topiramate daily from Sobhan Daru Company for one to a maximum of three weeks. The score of Opioid Withdrawal Syndrome in the Questionnaire. Timepoint: Before intervention and 3, 5, 7, 9 and 11 days after starting gabapentin or topiramate. Method of measurement: Subjective Opiate Withdrawal Scale. Fasa University of Medical Sciences Approved 2021-03-06 Ethics committee of Fasa University of Medical Sciences Ibn Sina Square, Fasa university of medical science Fasa Fars Iran (Islamic Republic of)