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IRCT201011275259N1 IRCT 2011-01-04 Deputy research of Zanjan University of Medical Sciences Prevention of infection after cesarean Comparison of single dose versus three doses antibiotic prophylaxis regimen for cesarean section 1996-10-01 anticipated 146 Complete https://irct.ir/trial/5608 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Infection following cesarean section. Intervention 1: Cefazolin 2 g/IV single-dose, in the operating room after clamping the umbilical cord. Intervention 2: Cefazolin 2 g/IV, three doses, after clamping the cord, 6 hours and 48 hours after cesarean section.
public Ahmadreza Mobaien
Department of Infectious Diseases, valiasr Hospital, Sheikh Fazlolah ave, Zanjan-Iran
Zanjan Iran (Islamic Republic of) +98 912 619 1730 amobaien@yahoo.com Zanjan University of Medical Sciences scientific Ahmadreza Mobaien
Department of Infectious Diseases, Valiasr Hospital, Sheikh Fazlolah ave, Zanjan-Iran
Zanjan Iran (Islamic Republic of) +98 912 619 1730 amobaien@yahoo.com Zanjan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: the number of vaginal examination of hospital stay less than or equal to four times, rupture of membranes for six hours or less, duration of hospitalization less than 24 hours, duration of surgery less than 60 minutes, gestational age more than 36 weeks, body mass index of less than 30. Exclusion criteria: Fever prior to cesarean section, urinary symptoms, no possibility to follow-up for 10 days after the operation, presence of underlying diseases such as diabetes and hypertension, receiving oral or intravenous antibiotics before surgery due to other causes, cesarean due to lack of progress in the second stage of labor, history of corticosteroid use 14 years 50 years Female T81.4 Infection following a procedure Prevention Prevention Cefazolin 2 g/IV single-dose, in the operating room after clamping the umbilical cord Cefazolin 2 g/IV, three doses, after clamping the cord, 6 hours and 48 hours after cesarean section Symptoms of infection. Timepoint: During the hospital stay after a cesarean every six hours and then discharged on day 10. Method of measurement: check of Of fever, chills, cellulitis incision, discharge and tenderness of uterine incision. Deputy research of Zanjan University of Medical Sciences Approved 2006-09-23 Deputy research of Zanjan University of Medical Sciences Deputy research of Zanjan University of Medical Sciences, Azadi Sq, Zanjan-Iran Zanjan Iran (Islamic Republic of)